Results 241 to 250 of about 72,751 (304)

Acyclic Nucleoside Phosphonates As Potential Inhibitors of Plasmodium Falciparum Egress

Chemistry – A European Journal, Volume 31, Issue 69, December 9, 2025.
Exploration of the chemistry of acyclic nucleoside phosphonates allowed us to study structural diversity from the hit compound; biological evaluation and molecular docking were performed to decipher key interactions with the putative target. Abstract The emergence of drug‐resistant Plasmodium strains requires the development of novel antimalarial ...
Thomas Cheviet, Sharon Wein, Corinne Lionne, Yan Badji, Natacha Venturini, Rachel Cerdan, Suzanne Peyrottes   +6 more
wiley   +1 more source

Purine metabolism in lung adenocarcinoma: A single-cell analysis revealing prognostic and immunotherapeutic insights. [PDF]

J Cell Mol Med
Zhang P, Pei S, Zhou G, Zhang M, Zhang L, Zhang Z.   +5 more
europepmc   +1 more source

Design, Optimized Synthesis, and Coordination Behavior of Quinolinic Benzimidazoles with Cu(II) and Ni(II): Reactivity Toward ROS, Computational Studies, and Biological Profiling

European Journal of Inorganic Chemistry, Volume 28, Issue 35, December 9, 2025.
Synthesis and characterization of quinolinic benzimidazole Cu(II) and Ni(II) complexes reveal contrasting reactive oxygen species interactions and selective anticancer activity, highlighting a prodrug‐like mechanism. This study provides new insights into designing redox‐active metal complexes for targeted cancer therapeutics Benzimidazole is a well ...
Lorenzo Verderi, Silvana Pinelli, Giorgio Pelosi, Franco Bisceglie   +3 more
wiley   +1 more source

STUDIES ON THE EFFECTS OF PURINES ON METABOLISM

Journal of Biological Chemistry, 1946
openaire   +2 more sources

Utilizing an integrated bioinformatics and machine learning approach to uncover biomarkers linking ulcerative colitis to purine metabolism-related genes. [PDF]

Heliyon
Chen T, Tao Y, Wang Q, Pei Y, Zhao Z, Yang W, Lu Y.   +6 more
europepmc   +1 more source

Integrated analysis of purine metabolism assists in predicting prognosis and treatment decisions for patients with lung adenocarcinoma. [PDF]

Heliyon
Zhang T, Chen R, Su X, Wang M, Lu Q.
europepmc   +1 more source