Results 211 to 220 of about 39,382 (265)

Crosstalk between purinergic receptor P2Y₁₁ and chemokine receptor CXCR7 is regulated by CXCR4 in human macrophages. [PDF]

Cell Mol Life Sci
Klaver D, Gander H, Frena B, Amato M, Thurnher M.   +4 more
europepmc   +1 more source

Ionotropic purinergic receptor 7 (P2X7) channel structure and pharmacology provides insight regarding non-nucleotide agonism. [PDF]

Channels (Austin)
Al-Aqtash R, Collier DM.
europepmc   +1 more source

Distribution of P2Y and P2X purinergic receptor expression within the intestine.

Am J Physiol Gastrointest Liver Physiol
Engevik KA, Scribano FJ, Gebert JT, Perry JL, Crawford SE, Hyser JM.   +5 more
europepmc   +1 more source

Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics. [PDF]

Mol Metab
Dance A, Fernandes J, Toussaint B, Vaillant E, Boutry R, Baron M, Loiselle H, Balkau B, Charpentier G, Franc S, Ibberson M, Marre M, Gernay M, Fadeur M, Paquot N, Vaxillaire M, Boissel M, Amanzougarene S, Derhourhi M, Khamis A, Froguel P, Bonnefond A.   +21 more
europepmc   +1 more source

Functions of Purinergic Receptors

, 2020
openaire   +1 more source

Radioligands targeting purinergic P2X7 receptor

Bioorganic and Medicinal Chemistry Letters, 2020
The purinergic P2X7 receptor (P2X7R) is an adenosine triphosphate (ATP) ligand-gated cationic channel receptor. P2X7R is closely associated with various inflammatory, immune, cancer, neurological, musculoskeletal and cardiovascular disorders. P2X7R is an
Qi-Huang Zheng
exaly   +2 more sources

Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile

Purinergic Signalling, 2021
Extracellular nucleotides act as danger signals that orchestrate inflammation by purinergic receptor activation. The expression pattern of different purinergic receptors may correlate with a pro- or anti-inflammatory phenotype.
J Merz, N Hoppe, Dennis Wolf
exaly   +2 more sources

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Platelet purinergic receptors

Current Opinion in Pharmacology, 2003
Activation of P2Y(1) and P2Y(12) receptors, through secreted ADP that is stimulated by agonists such as thrombin, thromboxane and collagen, is a major mechanism of platelet activation. P2X(1) receptors also participate in platelet shape change and potentiation of calcium mobilization.
Satya P, Kunapuli, Robert T, Dorsam, Soochong, Kim, Todd M, Quinton   +3 more
openaire   +2 more sources

Bladder Purinergic Receptors^a

Annals of the New York Academy of Sciences, 1990
In rabbits the contractile response of the urinary bladder is only partially due to cholinergic innervation since atropine does not completely block neuronally mediated contractions. In the human bladder this atropine resistance is controversial with some reporting atropine resistance in vitro while others have stated that the atropine resistance is ...
M R, Ruggieri, K E, Whitmore, R M, Levin
openaire   +2 more sources

Signaling at Purinergic P2X Receptors

Annual Review of Physiology, 2009
P2X receptors are membrane cation channels gated by extracellular ATP. Seven P2X receptor subunits (P2X1-7) are widely distributed in excitable and nonexcitable cells of vertebrates. They play key roles in inter alia afferent signaling (including pain), regulation of renal blood flow, vascular endothelium, and inflammatory responses.
Surprenant, Annmarie, Alan North, R.
openaire   +3 more sources