The Role of Purinergic Receptors in Cancer-Induced Bone Pain
Cancer-induced bone pain severely compromises the quality of life of many patients suffering from bone metastasis, as current therapies leave some patients with inadequate pain relief.
Sarah Falk+2 more
doaj +1 more source
The Role of Peripheral N‐Methyl‐D‐Asparate (NMDA) Receptors in Itch and Pain: A Narrative Review
ABSTRACT Background and Objective NMDA receptors, predominantly located in the central nervous system and known for their roles in synaptic plasticity and central sensitisation of pain and itch, are also expressed in peripheral sensory neurons. Emerging evidence suggests that peripheral NMDA receptors contribute to pathological pain and potentially ...
Ryusuke Tanaka+3 more
wiley +1 more source
Mitogenic Signaling by ATP/P2Y Purinergic Receptors in Astrocytes: Involvement of a Calcium-Independent Protein Kinase C, Extracellular Signal-Regulated Protein Kinase Pathway Distinct from the Phosphatidylinositol-Specific Phospholipase C/Calcium Pathway [PDF]
Joseph T. Neary+5 more
openalex +1 more source
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
Main Points AQP4ex and OAP‐forming AQP4M23 are expressed in non‐neuronal cells of the olfactory epithelium. AQP4ex‐KO and OAP‐null mice show reduced cell density, including OSNs, and impaired odor responses and behavior, with AQP4ex emerging as key regulator.
Donatella Lobraico+8 more
wiley +1 more source
Expression of Purinergic Receptor Channels and Their Role in Calcium Signaling and Hormone Release in Pituitary Gonadotrophs [PDF]
Melanija Tomić+3 more
openalex +1 more source
Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine
Main Points Astroglial CB1 mediate long‐term depression in the NAc through purine release. Amphetamine occludes LTD in male mice by inducing the saturation of A1 receptors. Astroglial CB1 mediate behavioral amphetamine effects in males, but not in females.
Yamuna Mariani+15 more
wiley +1 more source
The role of purinergic receptors in neural repair and regeneration after spinal cord injury. [PDF]
Cheng RD, Ren W, Luo BY, Ye XM.
europepmc +1 more source
Role of P2-purinergic receptors in rat Leydig cell steroidogenesis [PDF]
C. Foresta+5 more
openalex +1 more source
Revolutionizing Autoimmune Research: The Role of Caveolin‐1
ABSTRACT Introduction Caveolins (Cav) include Cav‐1, Cav‐2, and Cav‐3, with Cav‐1 being the most studied due to its prominent role as a major component of plasma membrane caveolae. Cav‐1 is involved in a wide range of cellular functions and plays a key role in regulating signaling pathways related to immune responses and inflammation.
Yanan Gao+8 more
wiley +1 more source