Results 211 to 220 of about 571,618 (248)

Role of purinergic receptors in the Alzheimer's disease. [PDF]

open access: yesPurinergic Signal, 2018
Cieślak M, Wojtczak A.
europepmc   +1 more source

PET Imaging of Purinergic Receptors

open access: yes, 2020
Over the recent years, interest in the purinergic signaling system has sparked in the field of positron emission tomography (PET). Purinergic receptors play key roles in physiological and pathological processes, although the exact role in these processes is not always fully understood.
Janssen, Bieneke   +2 more
openaire   +4 more sources

Platelet purinergic receptors

Current Opinion in Pharmacology, 2003
Activation of P2Y(1) and P2Y(12) receptors, through secreted ADP that is stimulated by agonists such as thrombin, thromboxane and collagen, is a major mechanism of platelet activation. P2X(1) receptors also participate in platelet shape change and potentiation of calcium mobilization.
Satya P, Kunapuli   +3 more
openaire   +2 more sources

Bladder Purinergic Receptorsa

Annals of the New York Academy of Sciences, 1990
In rabbits the contractile response of the urinary bladder is only partially due to cholinergic innervation since atropine does not completely block neuronally mediated contractions. In the human bladder this atropine resistance is controversial with some reporting atropine resistance in vitro while others have stated that the atropine resistance is ...
M R, Ruggieri, K E, Whitmore, R M, Levin
openaire   +2 more sources

Signaling at Purinergic P2X Receptors

Annual Review of Physiology, 2009
P2X receptors are membrane cation channels gated by extracellular ATP. Seven P2X receptor subunits (P2X1-7) are widely distributed in excitable and nonexcitable cells of vertebrates. They play key roles in inter alia afferent signaling (including pain), regulation of renal blood flow, vascular endothelium, and inflammatory responses.
Surprenant, Annmarie, Alan North, R.
openaire   +3 more sources

Purinergic receptors, prostacyclin and atherosclerosis

Pharmacological Research, 1992
Over the last decade, evidence has been provided that endothelial cells have a metabolic function in order to maintain blood vessel homeostasis. The endothelium releases relaxing and contracting factors in response to endogenous or exogenous substances such as acetylcholine, calcimycine, adenosine 5'triphosphate (ATP), bradykinin, arachidonic acid and ...
RAGAZZI, EUGENIO, CHINELLATO A.
openaire   +2 more sources

Purinergic and Glutamatergic Receptors on Astroglia

2014
Astroglial cells express many neurotransmitter receptors; the receptors to glutamate and ATP being the most abundant. Here, we provide a concise overview on the expression and main properties of astroglial glutamate receptors (ionotropic receptors represented by AMPA and NMDA subtypes) and metabotropic (mainly mGluR5 and mGluR3 subtypes) and ...
Verkhratsky, A; id_orcid 0000-0003-2592-9898   +1 more
openaire   +3 more sources

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