Results 221 to 230 of about 571,618 (248)
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Current Pharmaceutical Design, 2009
There is a brief summary of the early background literature about purinergic signalling and its involvement in pain, of ATP storage, release and ectoenzymatic breakdown and of the current classification of receptor subtypes for purines and pyrimidines. The review then focuses on purinergic mechanosensory transduction involved in visceral, cutaneous and
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There is a brief summary of the early background literature about purinergic signalling and its involvement in pain, of ATP storage, release and ectoenzymatic breakdown and of the current classification of receptor subtypes for purines and pyrimidines. The review then focuses on purinergic mechanosensory transduction involved in visceral, cutaneous and
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2002
Abstract The term purinergic receptor (or purinoceptor ) was first introduced to describe classes of membrane receptors that, when activated by either neurally released ATP (P2 purinoceptor ) or its breakdown product adenosine (P1 purinoceptor ), mediated relaxation of gut smooth muscle (Burnstock 1972, 1978).
Brian F King, Geoffrey Burnstock
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Abstract The term purinergic receptor (or purinoceptor ) was first introduced to describe classes of membrane receptors that, when activated by either neurally released ATP (P2 purinoceptor ) or its breakdown product adenosine (P1 purinoceptor ), mediated relaxation of gut smooth muscle (Burnstock 1972, 1978).
Brian F King, Geoffrey Burnstock
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Agonists and Antagonists for Purinergic Receptors
2019Membrane receptors that are activated by the purine nucleoside adenosine (adenosine receptors) or by purine or pyrimidine nucleotides (P2Y and P2X receptors) transduce extracellular signals to the cytosol. They play important roles in physiology and disease. The G protein-coupled adenosine receptors comprise four subtypes: A1, A2A, A2B, and A3.
Christa E, Müller +2 more
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Purinergic receptors in gastrointestinal inflammation
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2008Purinergic receptors comprise a family of transmembrane receptors that are activated by extracellular nucleosides and nucleotides. The two major classes of purinergic receptors, P1 and P2, are expressed widely in the gastrointestinal tract as well as immune cells.
Vasantha L, Kolachala +3 more
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Purinergic receptors in auditory neurotransmission
Hearing Research, 2003The effects of ATP (adenosine 5' triphosphate) analogs on gross cochlear potentials and single primary afferent discharge properties were studied by intracochlear perfusion in anesthetized guinea pigs. ATP-gamma-S was most potent, with betagammamethylene-ATP and Bz-ATP being significantly less effective.
T, Sueta +3 more
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Purinergic receptors in psychiatric disorders
Neuropharmacology, 2016Psychiatric disorders describe different mental or behavioral patterns, causing suffering or poor coping of ordinary life with manifold presentations. Multifactorial processes can contribute to their development and progression. Purinergic neurotransmission and neuromodulation in the brain have attracted increasing therapeutic interest in the field of ...
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The enteric purinergic P2Y1 receptor
Current Opinion in Pharmacology, 2006Significant recent discoveries have shown that the P2Y(1) purinergic receptor subtype is expressed in the enteric nervous system and at intestinal neuromuscular junctions. Secretomotor neurons, which release vasoactive intestinal peptide at their junctions with intestinal secretory glands, express the P2Y(1) receptor.
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Polish journal of pharmacology, 1997
The aim of the present paper was characterization of purinergic receptors specific for nucleotides (P2) and nucleosides (P1). Their subclassification, distribution and functions have been briefly described.
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The aim of the present paper was characterization of purinergic receptors specific for nucleotides (P2) and nucleosides (P1). Their subclassification, distribution and functions have been briefly described.
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Purinergic receptors modulators: An emerging pharmacological tool for disease management
Medicinal Research Reviews, 2022Jamshed Iqbal, Abid Mahmood
exaly