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CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct transcriptomic signatures associated with lupus. [PDF]
Zubiaur M +17 more
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Norepinephrine changes behavioral state via astroglial purinergic signaling
Chen AB +12 more
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The role of pannexin/purinergic signaling in intervascular communication from capillaries during skeletal muscle contraction in male Golden hamsters. [PDF]
Lamb IR, Novielli-Kuntz NM, Murrant CL.
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Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2012
AbstractThe concept of purinergic neurotransmission was proposed in 1972, after it was shown that adenosine 5′‐triphosphate (ATP) was a transmitter in non‐adrenergic, non‐cholinergic inhibitory nerves in the guinea pig taenia coli. Subsequently, ATP was identified as a cotransmitter in sympathetic and parasympathetic nerves, and it is now recognized ...
Burnstock, G., Verkhratsky, A.
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AbstractThe concept of purinergic neurotransmission was proposed in 1972, after it was shown that adenosine 5′‐triphosphate (ATP) was a transmitter in non‐adrenergic, non‐cholinergic inhibitory nerves in the guinea pig taenia coli. Subsequently, ATP was identified as a cotransmitter in sympathetic and parasympathetic nerves, and it is now recognized ...
Burnstock, G., Verkhratsky, A.
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Purinergic signaling and microglia
Pflügers Archiv - European Journal of Physiology, 2006Microglial cells are considered as the pathologic sensors of the brain. In this paper, we review mechanisms of purinergic signaling in microglia. As ATP is not only considered as a physiological signaling substance but is also elevated in pathology, it is not surprising that microglia express a variety of P2X, P2Y and adenosin receptors.
Katrin, Färber, Helmut, Kettenmann
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Purinergic signaling in thyroid disease
Purinergic Signalling, 2022It is known that thyroid hormones play pivotal roles in a wide variety of pathological and physiological events. Thyroid diseases, mainly including hyperthyroidism, hypothyroidism, and thyroid cancer, are highly prevalent worldwide health problems and frequently associated with severe clinical manifestations.
Ying Le, Donghui Lu, Meng Xue
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Glycogenolysis and Purinergic Signaling
2014Both ATP and glutamate are on one hand essential metabolites in brain and on the other serve a signaling function as transmitters. However, there is the major difference that the flux in the pathway producing transmitter glutamate is comparable to the rate of glucose metabolism in brain, whereas that producing transmitter ATP is orders of magnitude ...
Leif, Hertz, Junnan, Xu, Liang, Peng
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