Results 111 to 120 of about 7,573 (248)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

The anti-inflammatory astrocyte revealed: the role of the microbiome in shaping brain defences

open access: yesSignal Transduction and Targeted Therapy, 2021
Alexei Verkhratsky   +3 more
doaj   +1 more source

Role of purinergic receptors in the activation of human airway smooth muscle cells by the antimicrobial peptide LL-37

open access: yesEuropean Respiratory Review, 2006
Inflammatory cells that infiltrate and surround the airway smooth muscle (ASM) layer express antimicrobial peptides including the cathelicidin LL-37.
Suzanne Zuyderduyn   +3 more
doaj  

Purinergic receptors in skeletal muscles in health and in muscular dystrophy

open access: yes, 2014
The P2 purinergic (nucleotide) receptor super-family comprises of two families of protein. The P2X, which are channel-forming ionotropic receptors and the P2Y metabotropic receptors activating G protein-mediated signalling pathways.
Young, Christopher   +10 more
core  

Purinergic signalling in the genito-urinary tract. [PDF]

open access: yes, 2006
The main objective of this thesis was to examine the role of purinergic signalling in the contraction of the smooth muscle of the genito-urinary tract of laboratory animals and compare it to that of man.
Banks, F.C.L.
core  

Properties of ATP-gated ion channels assembled from P2X2 subunits in mouse cochlear Reissner’s membrane epithelial cells [PDF]

open access: yes, 2015
In the cochlea, Reissner’s membrane separates the scala media endolymphatic compartment that sustains the positive endocochlear potential and ion composition necessary for sound transduction, from the scala vestibuli perilymphatic compartment.
Cockayne, DA   +7 more
core   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli   +3 more
wiley   +1 more source

Postnatal developmental changes in the laryngeal chemosensory cell clusters of rats

open access: yesJournal of Anatomy, EarlyView.
Chemosensory cell clusters appeared in the rat larynx 2 days after birth and were already connected to afferent nerve fibers. Their number increased until 3 weeks of age, then stabilized while continuing to grow through the addition of new cells. Because their number reached a plateau around the time of weaning, their development may be linked to ...
Sayed Sharif Abdali   +5 more
wiley   +1 more source

Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence

open access: yesJournal of Periodontal Research, EarlyView.
Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno   +6 more
wiley   +1 more source

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