Results 201 to 210 of about 7,573 (248)
Hypoxia Modulates Platelet Purinergic Signalling Pathways. [PDF]
Paterson GG +11 more
europepmc +1 more source
Abstract figure legend Obesity and metabolic syndrome (MetS) are well‐known major risk factors for overactive bladder (OAB). Mechanisms underlying obesity‐/MetS‐associated OAB were explored using a high‐fat‐diet (HFD)‐induced obesity mouse model. HFD‐induced obesity/MetS mice developed an OAB phenotype characterized by enlarged non‐voiding contractions
Ayu Sugiura +3 more
wiley +1 more source
HIF‐Regulated Pannexin‐1 Channel Drives Luminal ATP Accumulation in Kidney Cysts
Autosomal dominant polycystic kidney disease causes progressive cyst enlargement in the kidneys, leading to hypoxia and induction of HIF‐1α. Our study identifies HIF‐1α‐dependent transcriptional upregulation of Pannexin1 (PANX1) in the apical membrane of cyst epithelial cells, promoting ATP release into the cyst lumen.
Kathrin Skoczynski +10 more
wiley +1 more source
Macrophage‐Fibroblast Crosstalk Shapes Wound Repair Signaling In Vitro
Intercellular communication between macrophages and fibroblasts is critical for wound healing. Macrophages promoted fibroblast scratch closure through contact‐dependent mechanisms independent of connexins. In contrast, fibroblasts regulated macrophage cytokine secretion via connexin‐43–mediated contact signaling that increased IL10 and paracrine ...
Daniela Enriquez‐Ochoa +12 more
wiley +1 more source
Purinergic Signalling in Parkinson's Disease: A Multi-target System to Combat Neurodegeneration. [PDF]
Tóth A +3 more
europepmc +1 more source
Purinergic signaling in cardiovascular system
Akiyuki, Nishimura, Motohiro, Nishida
openaire +3 more sources
Imbalance in the Expression of Genes Associated with Purinergic Signalling in the Lung and Systemic Arteries of COPD Patients. [PDF]
Careta O +7 more
europepmc +1 more source

