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Introduction to Purinergic Signalling in the Brain
2012ATP is a cotransmitter with glutamate, noradrenaline, GABA, acetylcholine and dopamine in the brain. There is a widespread presence of both adenosine (P1) and P2 nucleotide receptors in the brain on both neurons and glial cells. Adenosine receptors play a major role in presynaptic neuromodulation, while P2X ionotropic receptors are involved in fast ...
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Purinergic signaling at immunological synapses
Journal of the Autonomic Nervous System, 2000The early studies and hypotheses of Geoffrey Burnstock catalyzed intensive characterization of roles for nucleotides and P2 nucleotide receptors in neurotransmission and neuromodulation. These latter analyses have focused on the mechanisms of nucleotide release and action in the microenvironments of nerve endings and synapses.
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Purinergic signalling in cancer therapeutic resistance: From mechanisms to targeting strategies
Drug Resistance Updates, 2023Henning Ulrich +2 more
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Interplay between purinergic signalling and extracellular vesicles in health and disease
Biochemical Pharmacology, 2022Joost Hoenderop, Juan Pablo Rigalli
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Exploration of the link between gut microbiota and purinergic signalling
Purinergic Signalling, 2022Mingjian Li
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MicroRNA: Crucial modulator in purinergic signalling involved diseases
Purinergic Signalling, 2022Jing Guo, Shuguang Yu, Haiyan Yin
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More than a drug target: Purinergic signalling as a source for diagnostic tools in epilepsy
Neuropharmacology, 2023Tobias Engel
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