Results 191 to 200 of about 7,573 (248)

Brainstem Astrocytes Regulate Estrus‐Dependent Oscillations in Food Intake

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
DVC astrocytes regulate food intake and caloric balance via modulation of NMDA receptor‐mediated glutamatergic signaling to brainstem DMV motoneurons. In female rats, GFAP‐IR intensity and astrocyte morphological complexity increased during periods of high estrogen levels when food intake was decreased, and chemogenetic manipulation of DVC astrocytes ...
K. Selin Ozkaya   +4 more
wiley   +1 more source

Editorial: Purinergic pharmacology, Volume II

open access: yesFrontiers in Pharmacology, 2023
Francisco Ciruela   +2 more
doaj   +1 more source

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros   +6 more
wiley   +1 more source

Early Regional Microglial Remodelling in the Hippocampus of the AppNL‐G‐F Alzheimer's Model

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Microglia undergo profound structural and functional changes during Alzheimer's disease, yet the earliest stages of morphological remodelling that occur prior to amyloid deposition remain poorly defined. Through high‐resolution 3D morphometry in the CA1 region of the hippocampus of AppNL‐G‐F mice, it was found that although microglial numbers and ...
Ryan J. Bevan   +4 more
wiley   +1 more source

Acute Sleep Deprivation Shifts Substrate Utilization Toward Greater Fat Oxidation During Incremental Exercise in Recreationally Trained Adults

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 6, June 2026.
ABSTRACT Sleep deprivation alters metabolic homeostasis and substrate metabolism, but its effect on fat and carbohydrate utilization during exercise is unclear. This study examined the effects of one night of total and partial sleep deprivation on substrate utilization during a maximal fat oxidation test (MFO) in recreationally trained adults.
Marta del Val‐Manzano   +5 more
wiley   +1 more source

Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats

open access: yesThe Journal of Physiology, Volume 604, Issue 12, Page 4678-4706, 15 June 2026.
Abstract figure legend Exacerbated ATP signalling in the carotid body (CB) of spontaneously hypertensive rats (SHRs) arises from expansion of the chemosensory glomus cell compartment and reduced extracellular ATP metabolism, leading to increased purinergic drive.
Igor S. A. Felippe   +11 more
wiley   +1 more source

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