Results 171 to 180 of about 5,354,149 (260)

A Novel Catalytically Inactive Construct of Botulinum Neurotoxin A (BoNT/A) Directly Inhibits Visceral Sensory Signalling

Toxins
Botulinum neurotoxin A (BoNT/A) is a potent neurotoxin that silences cholinergic neurotransmission through the cleavage of the synaptic protein SNAP-25.
Hodan Ibrahim, Kevin Retailleau, Fraser Hornby, Jacquie Maignel, Matthew Beard, Donna Marie Daly   +5 more
doaj   +1 more source

Dysregulation of CD39/Ectonucleoside Triphosphate Diphosphohydrolase 1 Causes Urinary Bladder Dysfunction with Abnormal Smooth Muscle Contractility

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Abnormal extracellular ATP levels cause lower urinary tract symptoms (LUTS). Here, we demonstrate that overexpression of ENTPD1 (CD39TG)—an ATP/ADP converting enzyme—reduces voiding frequency while increasing void volume. Conversely, ENTPD1 deficiency results in frequent, small‐volume voiding.
Zhaobo Luo, Huan Chen, Ali Wu, Weipu Mao, Sagar Barge, Seth L. Alper, Simon C. Robson, Weiqun Yu   +7 more
wiley   +1 more source

EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling. [PDF]

Elife, 2022
Randzavola LO, Mortimer PM, Garside E, Dufficy ER, Schejtman A, Roumelioti G, Yu L, Pardo M, Spirohn K, Tolley C, Brandt C, Harcourt K, Nichols E, Nahorski M, Woods G, Williamson JC, Suresh S, Sowerby JM, Matsumoto M, Santos CXC, Kiar CS, Mukhopadhyay S, Rae WM, Dougan GJ, Grainger J, Lehner PJ, Calderwood MA, Choudhary J, Clare S, Speak A, Santilli G, Bateman A, Smith KGC, Magnani F, Thomas DC.   +34 more
europepmc   +1 more source

Editorial: Purinergic Signaling and Inflammation [PDF]

Frontiers in Immunology, 2021
Xiaoyi Yuan, Davide Ferrari, Tingting Mills, Yanyu Wang, Agnieszka Czopik, Marie-Francoise Doursout, Scott E. Evans, Marco Idzko, Holger K. Eltzschig   +8 more
openaire   +3 more sources

CNMa–CNMa receptor at microbiome–gut–brain axis: novel target to regulate feeding decision

Signal Transduction and Targeted Therapy, 2021
Liyuan Peng, Hai-Yan Yin, Canhua Huang
doaj   +1 more source

An introduction to the special issue "The contribution of pannexin-1, connexins and CALHM ATP-release channels to purinergic signalling". [PDF]

Purinergic Signal, 2021
Kennedy C.
europepmc   +1 more source

Purinergic Signalling in Allogeneic Haematopoietic Stem Cell Transplantation and Graft-versus-Host Disease. [PDF]

Int J Mol Sci, 2021
Cuthbertson P, Geraghty NJ, Adhikary SR, Bird KM, Fuller SJ, Watson D, Sluyter R.   +6 more
europepmc   +1 more source

The role of purinergic signalling in the musculoskeletal system [PDF]

Abbracchio, Agrawal, Alvarenga, Armstrong, Banachewicz, Berenbaum, Biswas, Biver, Bonewald, Bowler, Bowler, Bowler, Brandao-Burch, Brown, Buckley, Buckley, Buckley, Bulman, Burnstock, Burnstock, Burnstock, Burnstock, Buscher, Buvinic, Campo, Carroll, Caswell, Caswell, Chenu, Cheung, Choi, Chowdhury, Costa, Costessi, Croucher, Deli, Dixon, Evans, Ferrari, Fleisch, Fleisch, Fodor, Gartland, Gartland, Gartland, Gartland, Gartland, Genetos, Genetos, Gharibi, Gharibi, Graff, Graff, Grol, Hajjawi, Hayton, Hazama, He, Hecht, Hessle, Hiken, Hoebertz, Hoebertz, Hoebertz, Hollopeter, Hsu, Hung, Huo, Husted, Ihara, Isabel R. Orriss, Jande, Janssens, Janssens, Johnson, Jones, Jorgensen, Jorgensen, Jorgensen, Kanabe, Kaplan, Kaplan, Kara, Kara, Katz, Katz, Ke, Keresztes, Knight, Kono, Koolpe, Koolpe, Korcok, Korcok, Kringelbach, Kudirka, Kumagai, Kumagai, Lee, Leong, Leong, Lerner, Lerner, Li, Li, Liu, Mackenzie, Martinello, Masin, Mediero, Mediero, Meyer, Millward-Sadler, Morrison, Mortensen, Naemsch, Naemsch, Nakamura, Nicke, Nishii, Noronha-Matos, Noronha-Matos, Ohlendorff, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Panupinthu, Panupinthu, Pellegatti, Penolazzi, Pines, Ralevic, Reimer, Riddle, Romanello, Romanello, Rosenthal, Rumney, Ryan, Ryten, Schoenberg, Sciancalepore, Shimegi, Sistare, Su, Suzuki, Syberg, Syberg, Takedachi, Tesch, Thompson, Tu, Varani, Varani, Vincenzi, Voss, Wang, Wang, Wang, Weidema, Weidema, Wesselius, Wesselius, Wesselius, Wiebe, Wildman, You, Yu, Yu, Zimmermann, Zippel   +176 more
core   +1 more source

Two G protein-coupled receptors bind ceramides in atherosclerosis progression: targets for a new therapeutic strategy

Signal Transduction and Targeted Therapy
Yue Han, Peter Illes, Yong Tang
doaj   +1 more source

Editorial: “Purinergic Signaling 2020: The State-of-The-Art Commented by the Members of the Italian Purine Club”

Frontiers in Pharmacology, 2021
Francisco Ciruela, Francisco Ciruela, Kjell Fuxe, Peter Illes, Peter Illes, Henning Ulrich, Henning Ulrich, Francesco Caciagli   +7 more
doaj   +1 more source