Results 251 to 260 of about 53,976 (309)

ModE Regulates Alternative Nitrogenase Expression in the Methanogen Methanosarcina acetivorans

Molecular Microbiology, EarlyView.
During nitrogen fixation, the methanogen Methanosarcina acetivorans produces the alternative vanadium‐nitrogenase and iron‐nitrogenase only when molybdenum is unavailable to support the activity of molybdenum‐nitrogenase. Our work demonstrates that the expression of the alternative nitrogenases in M.
Melissa Chanderban, Daniel J. Lessner
wiley   +1 more source

Multicomponent Synthesis of C(8)-Substituted Purine Building Blocks of Peptide Nucleic Acids from Prebiotic Compounds. [PDF]

ChemistryOpen
Mancin E, Capecchi E, Botta L, Bizzarri BM.   +3 more
europepmc   +1 more source

Old Doubts From a New Perspective: Oral Versus Subcutaneous Methotrexate

International Journal of Dermatology, EarlyView.
Laura Kiss, Rolland Gyulai
wiley   +1 more source

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

Molecular Microbiology, EarlyView.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens, Ashley T. Deventer, Paul R. Johnston, Phillip T. Lowe, Alisdair B. Boraston, Joanne K. Hobbs   +5 more
wiley   +1 more source

Relationship between pyrimidines, purines, and fatty acids in milk of dairy cows fed distinct carbohydrate types: A metabolomic approach. [PDF]

JDS Commun
Giagnoni G, Weisbjerg MR, Errico M, Lapris M, Poulsen NA, Thomsen JPS, Gallo A, Rocchetti G.   +7 more
europepmc   +1 more source

An HWE‐Family Histidine Kinase Modulates Brucella Cell Envelope Properties and Host Innate Immune Response

Molecular Microbiology, EarlyView.
The HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Xingru Chen, Emily Perez, Eleanor C. Scheeres, Rosemary Northcote, Aretha Fiebig, Andrew J. Olive, Sean Crosson   +6 more
wiley   +1 more source

Assessing cross-national inequalities and predictive trends in gout burden: a global perspective (1990-2021). [PDF]

Front Med (Lausanne)
Li M, Nie Q, Xia Q, Jiang Z.
europepmc   +1 more source

Overview of pharmacodynamical research of traditional Chinese medicine on hyperuricemic nephropathy: from the perspective of dual-regulatory effect on the intestines and kidneys. [PDF]

Front Pharmacol
Wang T, Li L, Liu L, Tan R, Wu Q, Zhu X, Hua H, Dai Y, Li H, Mao J, Zhao J, Yin Z.   +11 more
europepmc   +1 more source

Novel Experimental Dietary Supplementations to Combat Metabolic Alterations in Diabetes. [PDF]

Nutrients
Rossell J, Julve J.
europepmc   +1 more source

Genetic Profiles of Purine, Uric Acid, Superoxide Dismutase, and Growth in Thai Slow-Growing Chickens. [PDF]

Animals (Basel)
Boonkum W, Chankitisakul V, Kananit S, Tuntiyasawasdikul V, Sirisan V, Kenchaiwong W.   +5 more
europepmc   +1 more source