Results 31 to 40 of about 36,659 (205)
A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output [PDF]
, 2015 Aerobic exercise, in spite of its multi-organ benefit and potent effect on the metabolome, has yet to be investigated comprehensively via an untargeted metabolomics technology.
Anthony, Nahoum +5 more
core +2 more sources
Journal of Biological Chemistry, 1912 "Reprinted from the Journal of biological chemistry, vol. XI, no. 3, 1912." ; "From the Rudolph Spreckels physiological laboratory of the University of California." ; Cover-title. ; Mode of access: Internet.
openaire +1 more source
Advanced Synthesis &Catalysis, Volume 367, Issue 5, March 4, 2025.Abstract Photochemical C−C coupling reactions can be tailored to industrial chemical processes and preparations of pharmaceuticals. Recent approaches in this area are limited to using precious transition metal coordination complexes that facilitate light absorption and redox processes with benchtop chemicals. Herein, we propose a paradigm that involves
Samjhana Maharjan +9 more
wiley +1 more source
Advanced Sensor Research, EarlyView.A one‐step electrochemical strategy is utilized to develop a flexible, enzyme‐free biosensor for the sensitive detection of uric acid (UA). The hierarchical cobalt nanostructures synergistically enhance the performance of the biosensor, resulting in a broad detection range of 5 to 700 µM with a sensitivity of 6.75 µA µM−1 cm−2 and a low detection limit
Anju Joshi, Gymama Slaughter
wiley +1 more source
Deep Supramolecular Language Processing for Co‐Crystal Prediction
Angewandte Chemie, EarlyView.DeepCocrystal is a deep learning model that predicts co‐crystal formation by learning supramolecular interactions from molecular string representations. It achieves high accuracy, estimates uncertainty, and offers interpretable insights into its predictions. Validated prospectively, DeepCocrystal discovered novel diflunisal co‐crystals and is available
Rebecca Birolo +5 more
wiley +2 more sources
Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]
, 2008 Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core
Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, EarlyView.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
Advanced Science, EarlyView.The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou +11 more
wiley +1 more source
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila +11 more
wiley +1 more source