A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]
, 2011 The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Atterbury, Alison, Wall, Mark J.
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Regularity, variabilty and bi-stability in the activity of cerebellar Purkinje cells
Frontiers in Cellular Neuroscience, 2009 Recent studies have demonstrated that the membrane potential of Purkinje cells is bi-stable and that this phenomenon underlies bi-modal simple spike firing.
Dan Rokni +3 more
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Climbing fiber regulation of spontaneous Purkinje cell activity and cerebellum-dependent blink responses [PDF]
, 2016 It has been known for a long time that GABAergic Purkinje cells in the cerebellar cortex, as well as their target neurons in the cerebellar nuclei, are spontaneously active.
Bengtsson, F. (Fredrik) +2 more
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Neurosteroid Biosynthesis and Action in the Purkinje Cell
Journal of Experimental Neuroscience, 2009 It is now clearly established that steroids can be synthesized de novo by the vertebrate brain. Such steroids are called neurosteroids. To understand neurosteroid action in the brain, data on the regio- and temporal-specific synthesis of neurosteroids ...
Kazuyoshi Tsutsui
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Neuropathological investigations of three murine models of Huntington’s disease [PDF]
, 2009 Huntington’s disease (HD) is a purely genetic neurodegenerative disorder affecting approximately 1 in 10,000 people. It is most commonly associated with excessive involuntary movement, or chorea, combined with varying degrees of other motor ...
Raza, A.S.
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Cell ReportsSummary: The loss of cerebellar Purkinje cells is a hallmark of neurodegenerative movement disorders, but the mechanisms remain enigmatic. We show that endocytic adaptor protein complex 2 (AP-2) is crucial for Purkinje cell survival. Using mouse genetics,
Marianna Tolve +14 more
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A Scalable Model of Cerebellar Adaptive Timing and Sequencing: The Recurrent Slide and Latch (RSL) Model [PDF]
, 2000 From the dawn of modern neural network theory, the mammalian cerebellum has been a favored object of mathematical modeling studies. Early studies focused on the fan-out, convergence, thresholding, and learned weighting of perceptual-motor signals within ...
Bullock, Daniel, Rhodes, Bradley
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Frontiers in Neuroanatomy, 2012 Between the first and the second postnatal week, the development of rodent Purkinje cells is characterized by several profound transitions. Purkinje cells acquire their typical dendritic espalier tree morphology and form distal spines.
Isabelle eDusart, Frédéric eFLAMANT
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Proceedings of Abstracts Engineering and Computer Science Research Conference 2019 [PDF]
, 2019 © 2019 The Author(s). This is an open-access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Adams, Roderick +81 more
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Cloning, expression, and localization of a rat brain high-affinity glycine transporter [PDF]
, 1992 A cDNA clone encoding a glycine transporter has been isolated from rat brain by a combined PCR and plaque-hybridization strategy. mRNA synthesized from this clone (designated GLYT1) directs the expression of sodium-and chloride-dependent, high-affinity ...
Brecha, Nicholas +4 more
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