Results 61 to 70 of about 5,279,387 (270)
Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells
iScience, 2022 Summary: Currently, there are no treatments that ameliorate cardiac cell death, the underlying basis of cardiovascular disease. An unexplored cell type in cardiac regeneration is cardiac Purkinje cells; specialized cells from the cardiac conduction ...
Nicole Prodan +11 more
doaj +1 more source
Cardiac morphological and morphometric analysis of Ardea alba
The Anatomical Record, EarlyView.Abstract Ardea alba (Linnaeus, 1758) is a widely distributed heron species whose cardiovascular morphology remains poorly described. This study aimed to characterize the cardiac morphology and morphometry of adult A. alba. Ten specimens were analyzed using radiographic, morphometric, histological, scanning electron microscopy, and three‐dimensional ...
Julia Vaz Feio +5 more
wiley +1 more source
The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum. [PDF]
PLoS ONE, 2008 The adult cerebellar cortex is comprised of reproducible arrays of transverse zones and parasagittal stripes of Purkinje cells. Adult stripes are created through the perinatal rostrocaudal dispersion of embryonic Purkinje cell clusters, triggered by ...
Matt Larouche +3 more
doaj +1 more source
Algorithm 4: Manage Purkinje cell fronts and Algorithm 5: Dendritic root initialization.
, 2023 Algorithm 4: Manage Purkinje cell fronts and Algorithm 5: Dendritic root initialization.
Erik De Schutter (29220) +1 more
core +1 more source
Clinical Anatomy, EarlyView.ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová +11 more
wiley +1 more source
Encoding of action by the Purkinje cells of the cerebellum [PDF]
Nature, 2015 Execution of accurate eye movements depends critically on the cerebellum, suggesting that the major output neurons of the cerebellum, Purkinje cells, may predict motion of the eye. However, this encoding of action for rapid eye movements (saccades) has remained unclear: Purkinje cells show little consistent modulation with respect to saccade amplitude ...
David J. Herzfeld +3 more
openaire +2 more sources
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Ataxic phenotype with altered CaV3.1 channel property in a mouse model for spinocerebellar ataxia 42
Neurobiology of Disease, 2019 Spinocerebellar ataxia 42 (SCA42) is a neurodegenerative disorder recently shown to be caused by c.5144G > A (p.Arg1715His) mutation in CACNA1G, which encodes the T-type voltage-gated calcium channel CaV3.1. Here, we describe a large Japanese family with
Shunta Hashiguchi +38 more
doaj +1 more source
Purkinje cell loss in essential tremor [PDF]
Movement Disorders, 2014 The recent study published by Symanski et al.1 reports similar Purkinje cell counts in a group of “essential tremor” cases compared to a group of controls. There are a number of major methodological problems with the design of the study and these problems cast doubt on the validity of the results that are reported.
Elan D, Louis, Phyllis L, Faust
openaire +2 more sources
Spinocerebellar ataxia:miRNAs expose biological pathways underlying pervasive Purkinje cell degeneration [PDF]
, 2017 Recent work has demonstrated the importance of miRNAs in the pathogenesis of various brain disorders including the neurodegenerative disorder spinocerebellar ataxia (SCA).
van der Stijl, Rogier +5 more
core +1 more source