Results 21 to 30 of about 12,043,245 (295)

Fear conditioning-related changes in cerebellar Purkinje cell activities in goldfish

Behavioral and Brain Functions, 2012
Background Fear conditioning-induced changes in cerebellar Purkinje cell responses to a conditioned stimulus have been reported in rabbits. It has been suggested that synaptic long-term potentiation and the resulting increases in firing rates of Purkinje
Yoshida Masayuki, Kondo Hiroki
doaj   +1 more source

Effect of gestational diabetes on neuronal cells in rat cerebellum in early postnatal life [PDF]

, 2014
Previous study has shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on rat cerebellum in early postnatal life. In this experimental
Ghafari, S., Golalipour, M.J., Hojati, V., Razi, E.M.   +3 more
core   +1 more source

Encoding of error and learning to correct that error by the Purkinje cells of the cerebellum

Nature Neuroscience, 2018
The primary output cells of the cerebellar cortex, Purkinje cells, make kinematic predictions about ongoing movements via high-frequency simple spikes, but receive sensory error information about that movement via low-frequency complex spikes (CS).
David J. Herzfeld, Y. Kojima, Robijanto Soetedjo, R. Shadmehr   +3 more
semanticscholar   +1 more source

Preterm Birth Impedes Structural and Functional Development of Cerebellar Purkinje Cells in the Developing Baboon Cerebellum

Brain Sciences, 2020
Human cerebellar development occurs late in gestation and is hindered by preterm birth. The fetal development of Purkinje cells, the primary output cells of the cerebellar cortex, is crucial for the structure and function of the cerebellum.
Tara Barron, Jun Hee Kim
doaj   +1 more source

Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells

Scientific Reports, 2018
Purkinje cells receive synaptic input from several classes of interneurons. Here, we address the roles of inhibitory molecular layer interneurons in establishing Purkinje cell function in vivo.
A. M. Brown, M. Arancillo, Tao Lin, Daniel R. Catt, Joy Zhou, Elizabeth P. Lackey, Trace L. Stay, Zhongyuan Zuo, Joshua J. White, R. Sillitoe   +9 more
semanticscholar   +1 more source

The Purkinje cell; 2008 style [PDF]

Journal of Molecular and Cellular Cardiology, 2008
Cardiac Purkinje fibers, due to their unique anatomical location, cell structure and electrophysiologic characteristics, play an important role in cardiac conduction and arrhythmogenesis. Purkinje cell action potentials are longer than their ventricular counterpart, and display two levels of resting potential.
Wen, Dun, Penelope A, Boyden
openaire   +2 more sources

The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum. [PDF]

PLoS ONE, 2008
The adult cerebellar cortex is comprised of reproducible arrays of transverse zones and parasagittal stripes of Purkinje cells. Adult stripes are created through the perinatal rostrocaudal dispersion of embryonic Purkinje cell clusters, triggered by ...
Matt Larouche, Uwe Beffert, Joachim Herz, Richard Hawkes   +3 more
doaj   +1 more source

Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

Journal of Neuroinflammation, 2009
Background Immunoglobulin G (IgG) antibodies reactive with intracellular neuronal proteins have been described in paraneoplastic and other autoimmune disorders.
Rose John W, Clawson Susan A, Hill Kenneth E, Carlson Noel G, Greenlee John E   +4 more
doaj   +1 more source

The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons

Frontiers in Aging Neuroscience, 2022
MRE11, RAD50, and NBS1 form the MRN complex in response to DNA damage to activate ATM, a gene responsible for Ataxia-Telangiectasia (A-T). Loss of any components of the MRN complex compromises cell life.
Mingmei Ding, Xiaobing Qing, Guangyu Zhang, Carolin Baade-Büttner, Ralph Gruber, Haizhen Lu, David O. Ferguson, Christian Geis, Zhao-Qi Wang, Zhao-Qi Wang, Zhong-Wei Zhou, Zhong-Wei Zhou   +11 more
doaj   +1 more source

Human cerebellar organoids with functional Purkinje cells. [PDF]

Cell Stem Cell
Atamian A, Birtele M, Hosseini N, Nguyen T, Seth A, Del Dosso A, Paul S, Tedeschi N, Taylor R, Coba MP, Samarasinghe R, Lois C, Quadrato G.   +12 more
europepmc   +2 more sources