Results 31 to 40 of about 4,460,775 (261)
Analysis of Microstructure of the Cardiac Conduction System Based on Three-Dimensional Confocal Microscopy. [PDF]
PLoS ONE, 2016 The specialised conducting tissues present in the ventricles are responsible for the fast distribution of the electrical impulse from the atrio-ventricular node to regions in the subendocardial myocardium.
Daniel Romero +3 more
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THE FINE STRUCTURE OF THE PURKINJE CELL [PDF]
The Journal of Cell Biology, 1963 This paper describes the fine structure of the Purkinje cell of the rat cerebellum after fixation by perfusion with 1 per cent buffered osmium tetroxide. Structures described include a large Golgi apparatus, abundant Nissl substance, mitochondria, multivesicular bodies, osmiophilic granules, axodendritic and axosomatic synapses, the nucleus, the ...
openaire +2 more sources
Remodeling of monoplanar Purkinje cell dendrites during cerebellar circuit formation.
PLoS ONE, 2011 Dendrite arborization patterns are critical determinants of neuronal connectivity and integration. Planar and highly branched dendrites of the cerebellar Purkinje cell receive specific topographical projections from two major afferent pathways; a single ...
Megumi Kaneko +9 more
doaj +1 more source
Quantification of the density of cooperative neighboring synapses required to evoke endocannabinoid signaling [PDF]
, 2014 The spatial pattern of synapse activation may impact on synaptic plasticity. This applies to the synaptically-evoked endocannabinoid-mediated short-term depression at the parallel fiber (PF) to Purkinje cell synapse, the occurrence of which requires ...
Pachoud, B +10 more
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Neural Development, 2010 Background Cerebellar corticogenesis begins with the assembly of Purkinje cells into the Purkinje plate (PP) by embryonic day 14.5 (E14.5) in mice. Although the dependence of PP formation on the secreted protein Reelin is well known and a prevailing ...
Miyata Takaki +7 more
doaj +1 more source
BK channels control cerebellar Purkinje and Golgi cell rhythmicity in vivo. [PDF]
PLoS ONE, 2009 Calcium signaling plays a central role in normal CNS functioning and dysfunction. As cerebellar Purkinje cells express the major regulatory elements of calcium control and represent the sole integrative output of the cerebellar cortex, changes in neural ...
Guy Cheron +6 more
doaj +1 more source
Initiation of simple and complex spikes in cerebellar Purkinje cells [PDF]
, 2010 Cerebellar Purkinje cells produce two distinct forms of action potential output: simple and complex spikes. Simple spikes occur spontaneously or are driven by parallel fibre input, while complex spikes are activated by climbing fibre input.
Clark, BA +14 more
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Specification of Granule Cells and Purkinje Cells.
, 2021 Granule cells and Purkinje cells are the major populations of neurons in the cerebellum. Their specification depends on a combination of regional identity and spatiotemporal cues.
Rook, Victoria +4 more
core +1 more source
Angewandte Chemie, EarlyView.Manganese‐modulated chemical exchange saturation transfer (CEST) MRI, Manga CEST, leverages intracellular Mn2+ uptake to selectively perturb CEST contrast. Comparing Z‐spectra before and after Mn reveals compartment‐specific contributions. In vivo, neuron‐enriched Mn accumulation induces frequency‐dependent attenuation (3–4 ppm), enabling cell‐weighted
Eleonora Cavallari +3 more
wiley +2 more sources
Thyroid Hormone Induces PGC-1α during Dendritic Outgrowth in Mouse Cerebellar Purkinje Cells
Frontiers in Cellular Neuroscience, 2017 Thyroid hormone 3,3′,5-Triiodo-L-thyronine (T3) is essential for proper brain development. Perinatal loss of T3 causes severe growth defects in neurons and glia, including strong inhibition of dendrite formation in Purkinje cells in the cerebellar cortex.
Tetsu Hatsukano +7 more
doaj +1 more source