Results 51 to 60 of about 303 (212)

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo   +13 more
wiley   +1 more source

A Class of Pursuit Problems in 3D Space via Noncooperative Stochastic Differential Games

open access: yesAerospace
This paper investigates three-dimensional pursuit problems in noncooperative stochastic differential games. By introducing a novel polynomial value function capable of addressing high-dimensional dynamic systems, the forward–backward stochastic ...
Yu Bai, Di Zhou, Zhen He
doaj   +1 more source

An Overview of Recent Advances in Pursuit–Evasion Games with Unmanned Surface Vehicles

open access: yesJournal of Marine Science and Engineering
With the rapid development of perception, decision-making, and control technologies, pursuit–evasion (PE) games with unmanned surface vehicles (USVs) have become an interesting research topic in military implementations and civilian areas. In this paper,
Xingru Qu   +4 more
doaj   +1 more source

EO-MADDPG: An Improved Reinforcement Learning Approach for Multi-UAV Pursuit–Evasion Games

open access: yesAerospace
To advance research in multi-agent reinforcement learning (MARL) for pursuit–evasion scenarios, this paper introduces a novel algorithm called Expert Knowledge and Opponent Modeling Multi-UAV Deep Deterministic Policy Gradient (EO-MADDPG).
Xiao Wang   +5 more
doaj   +1 more source

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

open access: yesThe Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

A Stackelberg Equilibrium-Based Control Algorithm for Satellite Sequential Pursuit-Evasion Gamesor

open access: yesAerospace
In long-range sequential orbital pursuit-evasion game scenarios, traditional Nash equilibrium algorithms rely on symmetric simultaneous decision-making assumptions.
Hao Liang   +3 more
doaj   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou   +10 more
wiley   +1 more source

Maneuver Planning for Multiple Pursuit Intelligent Surface Vehicles in a Sequence of Zero-Sum Pursuit–Evasion Games

open access: yesJournal of Marine Science and Engineering
Unmanned surface pursuit is a complex and challenging engineering problem, especially when conducted by multiple intelligent surface vehicles (ISVs). To enhance the pursuit performance and facilitate strategic interaction during the target pursuit, this ...
Le Hong   +4 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

Reciprocity on the Edge of Distance Paradox: How Sustainability Motives and Hypocrisy Shape Consumer Responses to Nearshoring

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Despite growing interest in corporate relocation decisions and sustainability, the existing literature is limited in its consumer‐centric approach. Integrating social exchange theory and construal level theory, this research investigates how consumers perceive sustainability‐driven nearshoring motives (i.e., socio‐economic vs.
Cagla Dayangan   +2 more
wiley   +1 more source

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