Results 81 to 90 of about 303 (212)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

COORDINATE-WISE INTEGRAL CONSTRAINT PURSUIT GAME OF STATE-TRANSITION MODELLED BY INFINITE SYSTEM OF TWO-COUPLED DIFFERENTIAL EQUATIONS

Barekeng
Pursuit-evasion games are pivotal in control theory, robotics, and autonomous systems, modelling adversarial interactions where agents operate under resource constraints.
Chika Samson Odiliobi, Risman Mat Hasim, Gafurjan Ibragimov   +2 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Pursuit-Evasion in Minimal Time with Varying Observation Constraints

Journal of Mathematical Sciences and Modelling
Optimal control problems under incomplete information, particularly in pursuit-evasion scenarios, present significant mathematical challenges. This study extends a basic time-optimal pursuit-evasion game by introducing a time-dependent observer parameter,
Özkan Değer
doaj   +1 more source

No Apologies? The Role of Apology for Structural‐Historical Injustice

Journal of Applied Philosophy, EarlyView.
ABSTRACT During this era of political apologies, a new literature has emerged in historical injustice interrogating the relationship between structural and historical injustice, with various theories conceptualising the relationship in different ways. Interestingly, ‘apology’ rarely appears in this literature.
Maeve McKeown
wiley   +1 more source

A Predictive Learning-Based Pursuit Strategy for the Multiple-to-One Orbital Pursuit–Evasion Game

Space: Science & Technology
The scarcity of space orbit resources has intensified the issue of orbital games between spacecraft. This paper presents a control strategy for the pursuing spacecraft in a multiple-to-one orbital pursuit–evasion game problem.
Peng Yan, Chengchao Bai, Mingjiang Ji, Hongxing Zheng, Ling Meng, Peng Wu, Lu Cao, Wei Pan, Xiaojun Ban   +8 more
doaj   +1 more source

Pursuit and Evasion Strategy of a Differential Game Based on Deep Reinforcement Learning. [PDF]

Front Bioeng Biotechnol, 2022
Xu C, Zhang Y, Wang W, Dong L.
europepmc   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

A weighted Stackelberg strategy approach for three pursuers against a superior evader using reinforcement learning

Journal of King Saud University: Computer and Information Sciences
Multi-player pursuit-evasion games under measurement noise are of great importance in aerospace and robotics. This paper investigates a differential game involving three cooperative pursuers and a single superior evader under system uncertainties.
Ziyi Zhan, Yiqun Zhang, Pengfei Zhang
doaj   +1 more source

Coping Practices of Small‐ and Medium‐Sized Enterprises Facing Power Asymmetry in Digital Platform Business

Strategic Change, EarlyView.
ABSTRACT Digital platform (DP) enterprises have risen to the top of the global economy by inverting traditional business models. They earn money through matchmaking, transaction facilitation, and efficient orchestration of other stakeholders' resources.
Lukas R. G. Fitz, Jochen Scheeg
wiley   +1 more source