Results 101 to 110 of about 6,124 (266)

Evasion in the plane [PDF]

Dynamic systems were considered subject to control by two agents, one of whom desires that no trajectory of the system emanating from outside a given set, intersects that set no matter what the admissible actions of the other agent.
Leitmann, G., Liu, H. S.
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A Deep Reinforcement Learning-Based Intelligent Maneuvering Strategy for the High-Speed UAV Pursuit-Evasion Game

Drones
Given the rapid advancements in kinetic pursuit technology, this paper introduces an innovative maneuvering strategy, denoted as LSRC-TD3, which integrates line-of-sight (LOS) angle rate correction with deep reinforcement learning (DRL) for high-speed ...
Tian Yan, Can Liu, Mengjing Gao, Zijian Jiang, Tong Li   +4 more
doaj   +1 more source

Barriers and dispersal surfaces in minimum-time interception [PDF]

Minimum time interception of a target moving in a horizontal plane is analyzed as a one-player differential game. Dispersal points and points on the barrier are located for a class of pursuit evasion and interception problems. These points are determined
Ardema, M. D., Rajan, N.
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Maneuver Planning for Multiple Pursuit Intelligent Surface Vehicles in a Sequence of Zero-Sum Pursuit–Evasion Games

Journal of Marine Science and Engineering
Unmanned surface pursuit is a complex and challenging engineering problem, especially when conducted by multiple intelligent surface vehicles (ISVs). To enhance the pursuit performance and facilitate strategic interaction during the target pursuit, this ...
Le Hong, Weicheng Cui, Hao Chen, Changhui Song, Weikun Li   +4 more
doaj   +1 more source

A formulation and analysis of combat games [PDF]

Combat is formulated as a dynamical encounter between two opponents, each of whom has offensive capabilities and objectives. With each opponent is associated a target in the event space in which he endeavors to terminate the combat, thereby winning.
Ardema, M. D., Heymann, M., Rajan, N.
core   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Linear Quadratic Pursuit–Evasion Games on Time Scales

Mathematics
In this paper, we unify and extend the linear quadratic pursuit–evasion games to dynamic equations on time scales. A mixed strategy for a single pursuer and evader is studied in two settings.
Davis Funk, Richard Williams, Nick Wintz
doaj   +1 more source