Results 51 to 60 of about 25,759 (281)

High-Speed Three-Dimensional Aerial Vehicle Evasion Based on a Multi-Stage Dueling Deep Q-Network

Aerospace, 2022
This paper proposes a multi-stage dueling deep Q-network (MS-DDQN) algorithm to address the high-speed aerial vehicle evasion problem. High-speed aerial vehicle pursuit and evasion are an ongoing game attracting significant research attention in the ...
Yefeng Yang, Tao Huang, Xinxin Wang, Chih-Yung Wen, Xianlin Huang   +4 more
doaj   +1 more source

An Introduction to Pursuit-evasion Differential Games [PDF]

2020 American Control Conference (ACC), 2020
Pursuit and evasion conflicts represent challenging problems with important applications in aerospace and robotics. In pursuit-evasion problems, synthesis of intelligent actions must consider the adversary's potential strategies. Differential game theory provides an adequate framework to analyze possible outcomes of the conflict without assuming ...
Weintraub, Isaac E., Pachter, Meir, Garcia, Eloy   +2 more
openaire   +2 more sources

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Game Tree Search-based Impulsive Orbital Pursuit–Evasion Game with Limited Actions

Space: Science & Technology
This paper focuses on the impulsive orbital pursuit–evasion game (OPEG) with limited action sets for the pursuer and evader. Initially, a mathematical model is developed by combining game theory and orbital dynamics, forming a finite-round impulsive OPEG
Wenyuan Xie, Liran Zhao, Zhaohui Dang
doaj   +1 more source

Pursuer’s Control Strategy for Orbital Pursuit-Evasion-Defense Game with Continuous Low Thrust Propulsion

Applied Sciences, 2019
This paper studies the orbital pursuit-evasion-defense problem with the continuous low thrust propulsion. A control strategy for the pursuer is proposed based on the fuzzy comprehensive evaluation and the differential game. First, the system is described
Junfeng Zhou, Lin Zhao, Jianhua Cheng, Shuo Wang, Yipeng Wang   +4 more
doaj   +1 more source

Active Target Defense Differential Game with a Fast Defender

, 2015
This paper addresses the active target defense differential game where an Attacker missile pursues a Target aircraft. A Defender missile is fired by the Target's wingman in order to intercept the Attacker before it reaches the aircraft.
Casbeer, David W., Garcia, Eloy, Pachter, Meir   +2 more
core   +1 more source

Pursuit–evasion games in the presence of obstacles [PDF]

Automatica, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Oyler, Dave W., Kabamba, Pierre T., Girard, Anouck R.   +2 more
openaire   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

An improved lion strategy for the lion and man problem

, 2017
In this paper, a novel lion strategy for David Gale's lion and man problem is proposed. The devised approach enhances a popular strategy proposed by Sgall, which relies on the computation of a suitable "center".
Casini, Marco, Garulli, Andrea
core   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source