Results 21 to 30 of about 1,914 (145)

Hypopituitarism after Orthohantavirus Infection: What is Currently Known? [PDF]

Viruses, 2019
Several case reports have described hypopituitarism following orthohantavirus infection, mostly following Puumala virus. The pathogenesis of this seemingly rare complication of orthohantavirus infection remains unknown.
Soerajja Bhoelan, Thomas Langerak, Danny Noack, Linda van Schinkel, Els van Nood, Eric C.M. van Gorp, Barry Rockx, Marco Goeijenbier   +7 more
doaj   +5 more sources

Host genetic factors associated with the range limit of a European hantavirus [PDF]

Molecular Ecology, Volume 31, Issue 1, Page 252-265, January 2022., 2022
The natural host ranges of many viruses are restricted to very specific taxa. Little is known about the molecular barriers between species that lead to the establishment of this restriction or generally prevent virus emergence in new hosts.
Heckel, Gerald, Labutin, Anton, Saxenhofer, Moritz, White, Thomas A.   +3 more
core   +2 more sources

Genotypic differentiation and evolutionary dynamics of puumala orthohantavirus (PUUV)

Acta Virologica
Puumala orthohantavirus (PUUV) is a causative agent of haemorrhagic fever with renal syndrome, mainly transmitted through rodent excretions. Classification of PUUV has traditionally been based on the geographic locations of their discovery, but this ...
Mariia A. Dashian, Ilya A. Volkhin, Pavel Yu. Volchkov, Pavel Yu. Volchkov, Pavel Yu. Volchkov, Andrei A. Deviatkin, Andrei A. Deviatkin   +6 more
doaj   +2 more sources

Cross-binding antibodies capable of neutralising diverse hantaviruses are produced in response to Puumala virus infection. [PDF]

EBioMedicine
Summary: Background: Orthohantaviruses (hantaviruses) are emerging rodent-borne pathogens that can cause severe human disease. They are present on multiple continents and are responsible for thousands of human cases per year.
Clark JJ, Hatzl S, Vasilev K, Andreata-Santos R, Yong JS, Mittler E, Kasikci E, Chandran K, Simon V, Krause R, Krammer F.   +10 more
europepmc   +2 more sources

Cells of the human respiratory tract support the replication of pathogenic Old World orthohantavirus Puumala [PDF]

Virology Journal, 2021
Background Transmission of all known pathogenic orthohantaviruses (family Hantaviridae) usually occurs via inhalation of aerosols contaminated with viral particles derived from infected rodents and organ manifestation of infections is characterized by ...
Stefan Hägele, Christian Nusshag, Alexander Müller, Alexandra Baumann, Martin Zeier, Ellen Krautkrämer   +5 more
doaj   +4 more sources

Characterization of the Puumala orthohantavirus Strains in the Northwestern Region of the Republic of Tatarstan in Relation to the Clinical Manifestations in Hemorrhagic Fever With Renal Syndrome Patients. [PDF]

Front Pharmacol, 2019
Over 1,000 cases of hemorrhagic fever with renal syndrome (HFRS) were recorded in the Republic of Tatarstan (RT) in 2015. HFRS is a zoonotic disease caused by several different Old World hantaviruses.
Davidyuk YN, Kabwe E, Shakirova VG, Martynova EV, Ismagilova RK, Khaertynova IM, Khaiboullina SF, Rizvanov AA, Morzunov SP.   +8 more
europepmc   +2 more sources

Impact of climate change on vector- and rodent-borne infectious diseases [PDF]

Journal of Health Monitoring, 2023
Background: Endemic and imported vector- and rodent-borne infectious agents can be linked to high morbidity and mortality. Therefore, vector- and rodent-borne human diseases and the effects of climate change are important public health issues.
Sandra Beermann, Gerhard Dobler, Mirko Faber, Christina Frank, Birgit Habedank, Peter Hagedorn, Helge Kampen, Carola Kuhn, Teresa Nygren, Jonas Schmidt-Chanasit, Erik Schmolz, Klaus Stark, Rainer G. Ulrich, Sabrina Weiss, Hendrik Wilking   +14 more
doaj   +5 more sources

Analysis of the relationship between replication of the Hokkaido genotype of Puumala orthohantavirus and autophagy

Virus Research, 2022
Hantaviruses are potentially fatal zoonotic pathogens of the family Hantaviridae. No human infection by the Hokkaido genotype of Puumala orthohantavirus (PUUV-Hok) has been reported.
Kazuma Tamiya, Shintaro Kobayashi, Kentaro Yoshii, Hiroaki Kariwa   +3 more
doaj   +3 more sources

Puumala Orthohantavirus Reassortant Genome Variants Likely Emerging in the Watershed Forests. [PDF]

Int J Mol Sci, 2023
Hemorrhagic fever with renal syndrome (HFRS) remains a prevalent zoonosis in the Republic of Tatarstan (RT), Russian Federation. Puumala orthohantavirus (PUUV), carried by bank voles (Myodes glareolus), is the principal zoonotic pathogen of HFRS in the RT.
Kabwe E, Shamsutdinov AF, Suleimanova S, Martynova EV, Ismagilova RK, Shakirova VG, Savitskaya TA, Isaeva GS, Rizvanov AA, Khaiboullina SF, Morzunov SP, Davidyuk YN.   +11 more
europepmc   +3 more sources

In silico design and evaluation of a multiepitope vaccine targeting the nucleoprotein of Puumala orthohantavirus

Proteins: Structure, Function, and Bioinformatics, Volume 92, Issue 10, Page 1161-1176, October 2024.
Abstract The Puumala orthohantavirus is present in the body of the bank vole (Myodes glareolus). Humans infected with this virus may develop hemorrhagic fever accompanying renal syndrome. In addition, the infection may further lead to the failure of an immune system completely.
Kunal Bhattacharya, Nongmaithem Randhoni Chanu, Saurav Kumar Jha, Pukar Khanal, Keshav Raj Paudel   +4 more
wiley   +3 more sources