Results 31 to 40 of about 1,914 (145)

Characterisation of Orthohantavirus Serotypes in Human Infections in Kazakhstan. [PDF]

Viruses
Orthohantavirus infection is a zoonotic disease transmitted to humans through contact with infected rodents. In Eurasia, Old World Orthohantaviruses can cause haemorrhagic fever with renal syndrome (HFRS), while in the Americas, New World ...
Tukhanova N, Shin A, Bakuli A, Yeraliyeva L, Maikanov N, Froeschl G, Zhumadilova Z, Tokmurziyeva G, Wagner E, Essbauer S, Peintner L.   +10 more
europepmc   +2 more sources

Orthohantaviruses, Emerging Zoonotic Pathogens [PDF]

Pathogens, 2020
Orthohantaviruses give rise to the emerging infections such as of hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) in Eurasia and the Americas, respectively.
Emmanuel Kabwe, Yuriy Davidyuk, Anton Shamsutdinov, Ekaterina Garanina, Ekaterina Martynova, Kristina Kitaeva, Moffat Malisheni, Guzel Isaeva, Tatiana Savitskaya, Richard A. Urbanowicz, Sergey Morzunov, Cyprian Katongo, Albert Rizvanov, Svetlana Khaiboullina   +13 more
doaj   +3 more sources

In-cell Western assay to quantify infection with pathogenic orthohantavirus Puumala virus in replication kinetics and antiviral drug testing

Virus Research, 2023
Hemorrhagic fever with renal syndrome (HFRS) represents a serious zoonotic disease caused by orthohantaviruses in Eurasia. A specific antiviral therapy is not available.
Christian Nusshag, Pamela Schreiber, Josephine Uhrig, Martin Zeier, Ellen Krautkrämer   +4 more
doaj   +3 more sources

Analysis of Puumala orthohantavirus Genome Variants Identified in the Territories of Volga Federal District. [PDF]

Trop Med Infect Dis, 2022
Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease commonly diagnosed in the Volga Federal District (VFD). HFRS is caused by Puumala orthohantavirus (PUUV), and this virus is usually detected in bank voles as its natural host (Myodes glareolus).
Kabwe E, Al Sheikh W, Shamsutdinov AF, Ismagilova RK, Martynova EV, Ohlopkova OV, Yurchenko YA, Savitskaya TA, Isaeva GS, Khaiboullina SF, Rizvanov AA, Morzunov SP, Davidyuk YN.   +12 more
europepmc   +5 more sources

Clinical and genomic characterisation of a fatal Puumala orthohantavirus case with low levels of neutralising antibodies. [PDF]

Infect Dis (Lond), 2022
Orthohantaviruses are rodent-borne emerging viruses that cause haemorrhagic fever with renal syndrome (HFRS) in Eurasia and hantavirus pulmonary syndrome in America. Transmission between humans have been reported and the case-fatality rate ranges from 0.4% to 40% depending on virus strain.
Tuiskunen Bäck A, Rasmuson J, Thunberg T, Rankin G, Wigren Byström J, Andersson C, Sjödin A, Forsell M, Ahlm C.   +8 more
europepmc   +4 more sources

Expression Profile of Human Renal Mesangial Cells Is Altered by Infection with Pathogenic Puumala Orthohantavirus. [PDF]

Viruses, 2022
Acute kidney injury (AKI) with proteinuria is a hallmark of infections with Eurasian orthohantaviruses. Different kidney cells are identified as target cells of hantaviruses. Mesangial cells may play a central role in the pathogenesis of AKI by regulation of inflammatory mediators and signaling cascades.
Nusshag C, Boegelein L, Schreiber P, Essbauer S, Osberghaus A, Zeier M, Krautkrämer E.   +6 more
europepmc   +4 more sources

Replication kinetics of pathogenic Eurasian orthohantaviruses in human mesangial cells. [PDF]

Virol J
Background Eurasian pathogenic orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by acute kidney injury (AKI). The virulence of orthohantaviruses varies enormously and direct infection of different renal cell types ...
Boegelein L, Schreiber P, Philipp A, Nusshag C, Essbauer S, Zeier M, Krautkrämer E.   +6 more
europepmc   +2 more sources

Puumala orthohantavirus genome sequence variations in the Republic of Tatarstan, Russia

International Journal of Infectious Diseases, 2020
E. Kabwe, Y. Davidyuk, A. Shamsutdinov, S. Morzunov, E. Martynova, E. Garanina, R. Ismagilova, A. Belyaev, E. Shuralev, G. Isaeva, S. Khaiboullina, A. Rizvanov   +11 more
doaj   +2 more sources

Rodent-Borne Orthohantaviruses in Vietnam, Madagascar and Japan

Viruses, 2021
Hantaviruses are harbored by multiple small mammal species in Asia, Europe, Africa, and the Americas. To ascertain the geographic distribution and virus-host relationships of rodent-borne hantaviruses in Japan, Vietnam, Myanmar, and Madagascar, RNAlater™-
Fuka Kikuchi, Kae Senoo, Satoru Arai, Kimiyuki Tsuchiya, Nguyễn Trường Sơn, Masaharu Motokawa, Marie Claudine Ranorosoa, Saw Bawm, Kyaw San Lin, Hitoshi Suzuki, Akira Unno, Keisuke Nakata, Masashi Harada, Keiko Tanaka-Taya, Shigeru Morikawa, Motoi Suzuki, Tetsuya Mizutani, Richard Yanagihara   +17 more
doaj   +1 more source

Hemorrhagic Fever with Renal Syndrome in Asia: History, Pathogenesis, Diagnosis, Treatment, and Prevention

Viruses, 2023
Hemorrhagic Fever with Renal Syndrome (HFRS) is the most frequently diagnosed zoonosis in Asia. This zoonotic infection is the result of exposure to the virus-contaminated aerosols.
Ayushi Sehgal, Sanya Mehta, Kritika Sahay, Ekaterina Martynova, Albert Rizvanov, Manoj Baranwal, Sara Chandy, Svetlana Khaiboullina, Emmanuel Kabwe, Yuriy Davidyuk   +9 more
doaj   +1 more source