Results 131 to 140 of about 12,669 (162)

Characterizing chlorotriazine effects in cancer-relevant high-throughput screening assays. [PDF]

Front Toxicol
Karmaus AL, Charlton A.
europepmc   +1 more source

Gut microbiota-metabolite interactions in drug-induced liver injury: mechanisms, biomarkers, and therapeutic perspectives. [PDF]

Front Cell Infect Microbiol
Mao X, Hu X, Fang J.
europepmc   +1 more source

The Pregnane-X receptor regulates steroid synthesis in mouse Leydig cells. [PDF]

Front Endocrinol (Lausanne)
Martinot E, Holota H, de Haze A, Beaudoin C, Volle DH.   +4 more
europepmc   +1 more source

Canine duodenal organoids as a functional platform for intestinal CYP regulation and drug metabolism studies. [PDF]

Drug Metab Dispos
Nakazawa M, Court MH, Ambrosini YM.
europepmc   +1 more source

Reduced ZMPSTE24 expression leads to prelamin accumulation and development of steatosis in MASLD patients. [PDF]

Sci Rep
Schinderle JD, Wu A, Bochkis IM.
europepmc   +1 more source

Bile acid regulation of xenobiotic nuclear receptors on the expressions of orosomucoids in the liver. [PDF]

Am J Physiol Endocrinol Metab
Suh JH, Cheon I, Jung HJ, Lee SH, Heo MJ, DeBerge M, Wooton-Kee CR, Kim KH.   +7 more
europepmc   +1 more source

Microbiota-Driven Strategies for Managing IBD-Associated Risks: From Infections to Mental Health. [PDF]

Pharmaceuticals (Basel)
Krynicka P, Cortegoso Valdivia P, Morawski M, Marlicz W, Skonieczna-Żydecka K, Koulaouzidis A.   +5 more
europepmc   +1 more source

Superior linear and comparable rotational protection of an air-filled helmet versus foam helmets. [PDF]

Sci Rep
Tan R, Baker CE, Yu X, Ghajari M.
europepmc   +1 more source

Comparative analysis of AI support levels in clinical interpretation of traumatic pelvic radiographs. [PDF]

NPJ Digit Med
Tee YS, Huang JF, Huang YT, Hsu CP, Chen HW, Hsieh CH, Fu CY, Cheng CT, Liao CH.   +8 more
europepmc   +1 more source

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Beyond CAR and PXR

Current Drug Metabolism, 2005
It is becoming increasingly evident that constitutive, induced, and regulated expression of genes important to the drug disposition process such as drug transporters, phase I and II metabolic enzymes are largely under the transcriptional control of certain nuclear receptor (NR) family members.
Santosh G, Dixit, Rommel G, Tirona, Richard B, Kim   +2 more
openaire   +2 more sources