Ferric uptake regulator Fur is conditionally essential in Pseudomonas aeruginosa [PDF]
, 2017 In Pseudomonas aeruginosa, the ferric uptake regulator (Fur) protein controls both metabolism and virulence in response to iron availability. Differently from other bacteria, attempts to obtain fur deletion mutants of P. aeruginosa failed, leading to the
Banin, Ehud +6 more
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Characterization of pyoverdine and achromobactin in
BMC Microbiology, 2011 Background Pseudomonas syringae pv. phaseolicola 1448a (P. syringae 1448a), the causative agent of bean halo blight, is a bacterium capable of occupying diverse biological niches. Under conditions of iron starvation P.
Owen Jeremy G, Ackerley David F
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Siderophore activity of pyoverdin for Pseudomonas aeruginosa [PDF]
Infection and Immunity, 1985 Pseudomonas aeruginosa produces an extracellular compound with yellowish green fluorescence, called pyoverdin, which functions as a siderophore. The production of pyoverdin, formerly called fluorescein, is concomitant with the production of another siderophore, pyochelin. Pyoverdin is produced by P.
C D, Cox, P, Adams
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Induction of systemic resistance to Botrytis cinerea in tomato by Pseudomonas aeruginosa 7NSK2 : role of salicylic acid, pyochelin, and pyocyanin [PDF]
, 2002 The rhizobacterium Pseudomonas aeruginosa 7NSK2 produces secondary metabolites such as pyochelin (Pch), its precursor salicylic acid (SA), and the phenazine compound pyocyanin. Both 7NSK2 and mutant KMPCH (Pch-negative, SA-positive) induced resistance to
Audenaert, Kris +3 more
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Cell aggregation promotes pyoverdine-dependent iron uptake and virulence in Pseudomonas aeruginosa
Frontiers in Microbiology, 2015 In Pseudomonas aeruginosa the Gac signaling system and the second messenger cyclic diguanylate (c-di-GMP) participate in the control of the switch between planktonic and biofilm lifestyles, by regulating the production of the two exopolysaccharides Pel ...
Daniela eVisaggio +7 more
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Virulence, 2020 Pseudomonas aeruginosa: causes serious infections in patients with compromised immune systems and exhibits resistance to multiple antibiotics. The rising threat of antimicrobial resistance means that new methods are necessary for treating microbial ...
Xu Wang +4 more
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Pyoverdine, the Major Siderophore in Pseudomonas aeruginosa, Evades NGAL Recognition
Interdisciplinary Perspectives on Infectious Diseases, 2012 Pseudomonas aeruginosa is the most common pathogen that persists in the cystic fibrosis lungs. Bacteria such as P. aeruginosa secrete siderophores (iron-chelating molecules) and the host limits bacterial growth by producing neutrophil-gelatinase ...
Mary E. Peek +3 more
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Optimised chronic infection models demonstrate that siderophore ‘cheating’ in Pseudomonas aeruginosa is context specific [PDF]
, 2017 The potential for siderophore mutants of Pseudomonas aeruginosa to attenuate virulence during infection, and the possibility of exploiting this for clinical ends, have attracted much discussion.
A Dötsch +89 more
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Illuminating Siderophore Transporter Functionality with Thiopeptide Antibiotics
mBio, 2023 The Gram-negative opportunistic pathogen Pseudomonas aeruginosa is a leading cause of infections and mortality in immunocompromised patients. This organism can overcome iron deprivation during infection via the synthesis of two iron-chelating ...
Stephen K. Dolan
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Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]
, 2017 Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio +8 more
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