Results 41 to 50 of about 12,133,346 (298)

Oscillatory Coupling of Hippocampal Pyramidal Cells and Interneurons in the Behaving Rat

open access: yesJournal of Neuroscience, 1999
We examined whether excitation and inhibition are balanced in hippocampal cortical networks. Extracellular field and single-unit activity were recorded by multiple tetrodes and multisite silicon probes to reveal the timing of the activity of hippocampal ...
J. Csicsvari   +4 more
semanticscholar   +1 more source

Axonal ramifications of hippocampal Ca1 pyramidal cells [PDF]

open access: yesThe Journal of Neuroscience, 1981
Intracellular injections of Lucifer Yellow into CA1 pyramidal cells of the in vitro guinea pig hippocampal slice enabled us to examine in detail the morphology of the axons of these neurons. We also recorded the electrophysiological responses of these neurons to alvear stimulation.
W D, Knowles, P A, Schwartzkroin
openaire   +2 more sources

Morphological Characteristics of Electrophysiologically Characterized Layer Vb Pyramidal Cells in Rat Barrel Cortex. [PDF]

open access: yesPLoS ONE, 2016
Layer Vb pyramidal cells are the major output neurons of the neocortex and transmit the outcome of cortical columnar signal processing to distant target areas. At the same time they contribute to local tactile information processing by emitting recurrent
Jochen F Staiger   +3 more
doaj   +1 more source

Age-dependent changes of p53 and p63 immunoreactivities in the mouse hippocampus

open access: yesLaboratory Animal Research, 2019
P53 and its family member p63 play important roles in cellular senescence and organismal aging. In this study, p53 and p63 immunoreactivity were examined in the hippocampus of young, adult and aged mice by using immunohistochemistry.
Tae-Kyeong Lee   +8 more
doaj   +1 more source

Axonal varicosity density as an index of local neuronal interactions. [PDF]

open access: yesPLoS ONE, 2011
Diffuse transmission is an important non-synaptic communication mode in the cerebral neocortex, in which neurotransmitters released from en passant varicosities interact with surrounding cells.
Zi-Wei Zhang   +2 more
doaj   +1 more source

Genes, Cells and Brain Areas of Intelligence

open access: yesFrontiers in Human Neuroscience, 2019
What is the neurobiological basis of human intelligence? The brains of some people seem to be more efficient than those of others. Understanding the biological foundations of these differences is of great interest to basic and applied neuroscience ...
Natalia A. Goriounova   +1 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

High temperatures alter physiological properties of pyramidal cells and inhibitory interneurons in hippocampus

open access: yesFrontiers in Cellular Neuroscience, 2012
Temperature has multiple effects on neurons, yet little is known about the effects of high temperature on the physiology of mammalian central neurons. Hyperthermia can influence behavior and cause febrile seizures.
Jennifer A. Kim, Barry W. Connors
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Von Economo Neurons in the Human Medial Frontopolar Cortex

open access: yesFrontiers in Neuroanatomy, 2018
The von Economo neurons (VEN) are characterized by a large soma, spindle-like soma, with little dendritic arborization at both, the basal and apical poles.
Carlos Arturo González-Acosta   +4 more
doaj   +1 more source

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