Results 41 to 50 of about 108,821 (298)
Key morphological features of human pyramidal neurons
Cerebral Cortex, 2023 AbstractThe basic building block of the cerebral cortex, the pyramidal cell, has been shown to be characterized by a markedly different dendritic structure among layers, cortical areas, and species. Functionally, differences in the structure of their dendrites and axons are critical in determining how neurons integrate information.
Benavides Piccione, Ruth +5 more
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Dynamic Moment Analysis of the Extracellular Electric Field of a Biologically Realistic Spiking Neuron [PDF]
, 2007 Based upon the membrane currents generated by an action potential in a biologically realistic model of a pyramidal, hippocampal cell within rat CA1, we perform a moment expansion of the extracellular field potential.
Koch, Christof, Milstein, J. N.
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Six networks on a universal neuromorphic computing substrate [PDF]
, 2013 In this study, we present a highly configurable neuromorphic computing substrate and use it for emulating several types of neural networks. At the heart of this system lies a mixed-signal chip, with analog implementations of neurons and synapses and ...
Andreas eGrübl +10 more
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, 2015 Background: Recent genome-wide association studies (GWAS) have identified a large number of genetic risk factors for schizophrenia (SCZ) featuring ion channels and calcium transporters.
Andreassen, Ole A. +9 more
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An inhibitory pull-push circuit in frontal cortex. [PDF]
, 2017 Push-pull is a canonical computation of excitatory cortical circuits. By contrast, we identify a pull-push inhibitory circuit in frontal cortex that originates in vasoactive intestinal polypeptide (VIP)-expressing interneurons.
AA Zekveld +26 more
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Frontiers in Computational Neuroscience, 2019 Pyramidal cells in layer V of the neocortex are one of the most widely studied neuron types in the mammalian brain. Due to their role as integrators of feedforward and cortical feedback inputs, they are well-positioned to contribute to the symptoms and ...
Tuomo Mäki-Marttunen +9 more
doaj +1 more source
eLife, 2020 Vasoactive intestinal peptide-expressing (VIP) interneurons in the cortex regulate feedback inhibition of pyramidal neurons through suppression of somatostatin-expressing (SST) interneurons and, reciprocally, SST neurons inhibit VIP neurons. Although VIP
Daniel J Millman +15 more
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Neurons and circuits for odor processing in the piriform cortex [PDF]
, 2013 Increased understanding of the early stages of olfaction has lead to a renewed interest in the higher brain regions responsible for forming unified ‘odor images’ from the chemical components detected by the nose.
Bekkers, John MacDonald +1 more
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Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Predicting the synaptic information efficacy in cortical layer 5 pyramidal neurons using a minimal integrate-and-fire model [PDF]
, 2008 Synaptic information efficacy (SIE) is a statistical measure to quantify the efficacy of a synapse. It measures how much information is gained, on the average, about the output spike train of a postsynaptic neuron if the input spike train is known. It is
Häusser, M., Larkum, M.E., London, M.
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