Results 51 to 60 of about 108,821 (298)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Atypical hippocampal excitatory neurons express and govern object memory
Nature CommunicationsClassically, pyramidal cells of the hippocampus are viewed as flexibly representing spatial and non-spatial information. Recent work has illustrated distinct types of hippocampal excitatory neurons, suggesting that hippocampal representations and ...
Adrienne I. Kinman +17 more
doaj +1 more source
Logarithmic distributions prove that intrinsic learning is Hebbian
, 2017 In this paper, we present data for the lognormal distributions of spike rates, synaptic weights and intrinsic excitability (gain) for neurons in various brain areas, such as auditory or visual cortex, hippocampus, cerebellum, striatum, midbrain nuclei ...
Scheler, Gabriele
core +2 more sources
Physiological sharp wave-ripples and interictal events in vitro: What’s the difference? [PDF]
, 2014 Sharp wave-ripples and interictal events are physiological and pathological forms of transient high activity in the hippocampus with similar features.
Freund, Tamás +7 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Nociceptive Processing by Anterior Cingulate Pyramidal Neurons
Journal of Neurophysiology, 2010 Although the cingulate cortex is frequently activated in acute human pain studies, postsynaptic responses are not known nor are links between nociceptive afferents, neuronal responses, and outputs to other structures. Intracellular potentials were recorded from neurobiotin-injected, pyramidal neurons in anterior cingulate area 24b following noxious ...
Bai-Chuang, Shyu +3 more
openaire +3 more sources
Properties of Layer 6 Pyramidal Neuron Apical Dendrites [PDF]
The Journal of Neuroscience, 2010 Layer 6 (L6) pyramidal neurons are the only neocortical pyramidal cell type whose apical dendrite terminates in layer 4 rather than layer 1. Like layer 5 pyramidal neurons, they participate in a feedback loop with the thalamus and project to other cortical areas.
Ledergerber, Debora +1 more
openaire +3 more sources
Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
Nature Communications, 2018 While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection
Luping Yin +12 more
doaj +1 more source
Genetic Single Neuron Anatomy Reveals Fine Granularity of Cortical Axo-Axonic Cells
Cell Reports, 2019 Summary: Parsing diverse nerve cells into biological types is necessary for understanding neural circuit organization. Morphology is an intuitive criterion for neuronal classification and a proxy of connectivity, but morphological diversity and ...
Xiaojun Wang +18 more
doaj +1 more source
Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations [PDF]
, 2003 Electrical coupling between pyramidal cell axons, and between interneuron dendrites, have both been described in the hippocampus. What are the functional roles of the two types of coupling?
Bibbig, A. +7 more
core +2 more sources