Results 91 to 100 of about 7,109 (211)

Enhanced CO Selectivity in CO2 Electroreduction on Pyrazole‐Modified Boron‐Doped Diamond Electrodes

ChemElectroChem, Volume 13, Issue 6, 17 March 2026.
Electrochemical CO2 reduction is demonstrated using molecularly modified boron‐doped diamond electrodes. Pyrazole modification doubles the CO selectivity compared to the previous aniline‐modified surface. This enhancement arises from the synergistic effect of the adjacent nitrogen atoms in pyrazole, which provides both high nucleophilicity for CO2 ...
Ekitomo Oh, Yasuaki Einaga, Takashi Yamamoto   +2 more
wiley   +1 more source

Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso, José A. Paixão, Teresa M. V. D. Pinho e Melo   +2 more
wiley   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Synthesis of Heterocyclic Compounds Derived from 2-Mercapto Quinoline

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
2-Mercapto quinoline was used as precursor for synthesis of new heterocyclic derivatives of quinoline nucleus such as pyrazole (3), pyrazolone (4), 1,3,4-oxadiazole (5) and 1,2,4-triazole (8). New Schiff bases (9a-e) were obtained from the reaction of
A. H. Sharba, H. A. Hassan, D. F. Hassan
doaj  

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Crystal Engineering of Reticular Materials for Gas‐ and Liquid‐Phase Hydrocarbon Separation

Advanced Materials, Volume 38, Issue 16, 17 March 2026.
Crystal engineering enables systematic study of structure/function relationships as exemplified by pore engineering of reticular sorbents, including porous coordination networks and covalent organic frameworks. This review assesses such studies applied across the full scope of industrially relevant hydrocarbon separations to provide insight into how ...
Xia Li, Soumya Mukherjee, Michael J. Zaworotko   +2 more
wiley   +1 more source

Design, synthesis, and bioevaluation of pyrazole-containing tubulin polymerisation inhibitors based on conformational constraint strategy

Journal of Enzyme Inhibition and Medicinal Chemistry
Based on conformational preference of SMART analogues and conformational constraint strategy, two series of new tubulin polymerisation inhibitors (4a − 4k and 5a − 5h/6a − 6h) were designed via hydrogen bonding, steric effect (for 4a − 4k) and ring ...
Zhongqiao Sun, Jiahao Wang, Fengwei Li, Liancheng Huang, Shide Zheng, Qi Guan, Zhaohua Wang, Weige Zhang   +7 more
doaj   +1 more source

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao, Bo‐Kai Su, Ying‐Jan Wang, Ting‐Yuan Tu   +3 more
wiley   +1 more source

Development and systematic evaluation of triamine‐based functional deep eutectic solvents for efficient CO2 capture

AIChE Journal, Volume 72, Issue 3, March 2026.
Abstract The development of advanced absorbents for effectively capturing carbon dioxide is crucial in mitigating greenhouse gas emissions. This study introduced a series of deep eutectic solvents (DESs) for CO2 capture and identified the most promising DESs with the stepwise screening method based on their absorption capacity, absorption rate, thermal
Qiangbing Shi, Kaige Jia, Xiangping Zhang, Chuan Wang, Paul Cobden, Anna‐Maria Beregi Amnéus, David Muren, Xiaoyan Ji   +7 more
wiley   +1 more source

Mausolate Complexes of the Alkaline Earth Metals

ChemistryEurope, Volume 4, Issue 3, March 2026.
Reliable chelation of Ra2+ for radionuclide therapy has long been a challenge, and the capacious and rigid mausolate ligand may offer a promising approach. We describe herein mausolate complexes with the chemically similar Ba2+, and other group 2 dications, including the introduction of functionalized derivatives. The rapid uptake of alkaline earth (Ae)
Jack F. Smart, Liam D. N. Krueckl, R. Quinn Schmidt, Leah Gajecki, Lindsey E. K. Frederiksen, Allen G. Oliver, David J. Berg, J. Scott McIndoe   +7 more
wiley   +1 more source