Results 111 to 120 of about 340,649 (242)

The Effect of Nano-Pyrazole Derivative of Thiosemicarbazone Magnetite on BRCA1, p53 and Bcl-2 Gene Expression in MCF-7 Breast Cancer Cell Line

Journal of Ardabil University of Medical Sciences, 2019
Background & objectives: Breast cancer is one of the most important causes of cancer deaths especially in developing countries. However, some synthetic compounds such as thiosemicarbazone and its metal derivatives can play a very significant role in ...
Mohammad Reza Izadpanah, Ali Saleh zadeh, Mohammad Zaiefi zadeh, Mohammad Nik pasand   +3 more
doaj  

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Synthesizes Azo derivatives linked 1,2,3-triazols ring and studying their biological activity

Muthanna Journal of Pure Science
In this  research we studied the synthesis of  Azo derivatives which linked 1,2,3-triazols ring and studying the biological activity of this derivatives.
Afraah dawod
doaj   +1 more source

A Versatile Heterometallic Microporous MOF for Photocatalytic Hydrogen Generation

Small, EarlyView.
This work describes a green and scalable approach to robust and flexible heterometallic MOFs, MIP‐215's, with tunable photoactivity for efficient, noble‐metal‐free solar hydrogen production. ABSTRACT Photocatalytic particulate systems offer a cost‐effective solar hydrogen production but are generally limited by narrow visiblelight absorption and poor ...
Xingze Wang, Juan José Ramírez‐Hernández, Iurii Dovgaliuk, Valentin Diez Cabanes, Debanjan Chakraborty, Herme G. Baldoví, Hermenegildo García, Guillaume Maurin, Sergio Navalon, Georges Mouchaham, Christian Serre   +10 more
wiley   +1 more source

Synthesis and therapeutic evaluation of isatin-linked pyrazole motif derivatives

Multi-target drugs possess significant therapeutic potential for the therapy of complex diseases and drug-resistant conditions. Based on this fact, isatin-pyrazole derivatives, namely, 5-substituted isatin-pyrazole derivatives 7a-d and N-alkyl isatin ...
Hamad M. Alkahtani, Mashooq A. Bhat, Hazem A. Ghabbour, Ahmed M. Naglah, Mohamed A. Al-Omar, Ashraf S. Hassan, Abdulrahman A. Almehizia, Wael M. Aboulthana   +7 more
core   +1 more source

‐pyrazole‐3‐carboxylic acid

, 2002
The 1H-pyrazole-3-carboxylic acid 2, obtained from the furan-2,3-dione 1 and N-Benzylidene-N'-(3-nitrophenyl) hydrazine, was converted via reactions of its acid chloride 3 with various alcohols or N-nucleophiles into the corresponding ester or amide ...
Rahmi Kasimogullari, Yunus Akçamur, Ishak Bildmci, Sener, MK, Akcamur, Y, Kasimogullari, R, Ahmet Şener, Sener, A, Bildirici, I, M. Kasim Şener   +9 more
core   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Synthesis and Anti-Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds

Molecules
Chagas disease, a silent but widespread disease that mainly affects a socioeconomically vulnerable population, lacks innovative safe drug therapy. The available drugs, benznidazole and nifurtimox, are more than fifty years old, have limited efficacy, and
Thamyris Perez de Souza, Lorraine Martins Rocha Orlando, Leonardo da Silva Lara, Vitoria Barbosa Paes, Lucas Penha Dutra, Mauricio Silva dos Santos, Mirian Claudia de Souza Pereira   +6 more
doaj   +1 more source

Complex Chemistry of a Chiral Terpyridine Ligand Based on (1R)‐(+)‐Camphor

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
From (1R)‐(+)‐camphor, a chiral terpyridine ligand is accessible in a few steps that coordinates to divalent metal ions of the first and second transition metal row. From structural characterization, the steric repulsion of the two equatorial methyl groups of the tetrahydromethanoquinoline units becomes evident, which causes cyclometalation of the ...
Julia Ehrhard, Marc H. Prosenc, Werner R. Thiel   +2 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources