Results 121 to 130 of about 7,294 (164)

Nucleophilic cyclization of <i>N</i>-propargylated pyrazole-5-carboxylates: synthesis of pyrazolo[1,5-<i>a</i>]pyrazin-4(5<i>H</i>)-one derivatives. [PDF]

Turk J Chem
Mengeş MF, Tan Uygun M.
europepmc   +1 more source

Efficient Access to Functionalized <i>N</i>‑Difluoromethylpyrazoles. [PDF]

ACS Omega
Ugrak B, Dutova T, Rusak V, Xia D, Tretyakov E.   +4 more
europepmc   +1 more source

A patent review of cyclin-dependent kinase 5 (CDK5) inhibitors (1999-2025). [PDF]

Front Bioeng Biotechnol
Derzhavina VM, Khalymbadzha IA, Yuzhalin AE.   +2 more
europepmc   +1 more source

Revisiting Hydrazine Moiety as a Scaffold for the Synthesis of Potential Antiviral Pyrazole Ribonucleoside Analogues. [PDF]

ChemMedChem
Guillou A, Gros N, Muriaux D, Peyrottes S, Vasseur JJ, Smietana M, Mathé C.   +6 more
europepmc   +1 more source

Pyrazole/pyrimidine derivatives endowed with azobenzenes as dual EGFR^T790M and VEGFR-2 inhibitors: anticancer, docking, synthesis, design and ADMET assessments. [PDF]

RSC Adv
Anwer KE, Abdelgawad MA, Abdulhaleem M FA, Abd El-Sattar NEA, El-Morsy A, Nasr T, Elmowafy M, El-Adl K, Ahmed NM.   +8 more
europepmc   +1 more source

Integrated synthesis, antiproliferative potential, and <i>in silico</i> analysis of novel pyrazole-based hydrazones derived from 3-(2-(4-chlorophenyl)hydrazineylidene)-5-phenylfuran-2(3<i>H</i>)-one. [PDF]

RSC Adv
Ramadan SK, Kazem MSH, Kamal M, Hashem AI, Abd-Rabboh HSM, Abou-Elmagd WSI.   +5 more
europepmc   +1 more source

Development of new pyrazole-thiophene hybrids: synthesis, anticancer assessment, and molecular docking insights. [PDF]

RSC Adv
Samy S, Mahmoud SE, Abdel-Galil E, Abdel-Latif E, Said GE.   +4 more
europepmc   +1 more source

Design, synthesis, and mechanistic evaluation of novel pyrazole/thiazole chalcone hybrids as dual tubulin polymerization and COX-2 inhibitors with potent antiproliferative activity. [PDF]

RSC Adv
Saleem BAA, Qurtam AA, Shalabi AR, Al-Zharani M, Abass KS, Bräse S, Alotaibi G, Alkhammash A.   +7 more
europepmc   +1 more source

Design, synthesis, characterization, pharmacological evaluation and in silico ADMET and molecular docking and dynamics simulations of a novel series of N-substituted pyrazole from chalcone derivatives. [PDF]

Sci Rep
Hafez HN, Otaif HY, Alshammari BH, Alhebshe NS, El-Sayed AF, Abbas HS, Ammar RA.   +6 more
europepmc   +1 more source

Optimization of Antifungal 1,5-Diaryl-Pyrazole Acetyl-CoA Synthetase Inhibitors. [PDF]

ACS Omega
Propp JP, Ferreira JC, Enayati P, Alden KM, Daraji DG, Lail CL, Heene ME, Jezewski AJ, Wakade R, Castor D, Williams NS, Hagen TJ, Krysan DJ.   +12 more
europepmc   +1 more source