Results 101 to 110 of about 15,610 (266)

Rapid Discovery of Pyrido[3,4- d ]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach [PDF]

, 2016
Monopolar spindle 1 (MPS1) plays a central role in the transition of cells from metaphase to anaphase and is one of the main components of the spindle assembly checkpoint.
Baker, R, Blagg, J, Box, G, Burke, R, Cronin, N, De Haven Brandon, A, Eccles, SA, Faisal, A, Hayes, A, Henley, AT, Hoelder, S, Innocenti, P, Linardopoulos, S, Mak, GW-Y, Matijssen, B, Naud, S, O’Fee, L, Raynaud, FI, Roberts, J, Saville, H, Schmitt, J, Solanki, S, Valenti, M, van Montfort, RLM, Westwood, IM, Woodward, HL   +25 more
core   +2 more sources

Iridium Complexes of a Triazole‐Derived Pincer Ligand: Synthesis, Reactivity, and Transfer Dehydrogenation Catalysis

Chemistry – A European Journal, EarlyView.
Ir pincer complexes bearing a triazole architecture in the pincer backbone and O‐ancillary chelating ligands are presented. These were employed in the catalytic transfer dehydrogenation of alkanes as well as of saturated heterocycles. Reactivity of these complexes with silver salts and Lewis acids produced various cationic iridium complexes.
Jesvita Cardozo, Ouchan He, Aaron Prenzlow, Xinyang Peng, Kallol Ray, Thomas Braun   +5 more
wiley   +1 more source

Synthesis of fluorescently labeled pyrazole derivative induceing a triple response in Arabidopsis seedlings. [PDF]

J Pestic Sci, 2022
Oh K, Jiang K.
europepmc   +1 more source

Key Intermediates: A simple and Highly Selective Synthesis of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles for Applications in the Crop Protection [PDF]

, 2015
A series of six pyrazoles was synthesized by Michael-type addition reaction. The molecules 5- amino-1-aryl-1H-pyrazole-4-carbonitrile (3a-f) were synthesized from (ethoxymethylene)malononitrile (1) and fluorinated and non-fluorinated aryl hydrazines (2a ...
Murguia, Marcelo Cesar, Müller, Diana, Plem, Silvana Cristina   +2 more
core   +2 more sources

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

N-{2-[2-(5-Methyl-1H-pyrazol-3-yl)acetamido]phenyl}benzamide monohydrate

IUCrData, 2017
The asymmetric unit of the title compound, C19H18N4O2·H2O, comprises the U-shaped pyrazole derivative and a solvent water molecule. The molecular conformation is partly determined by an intramolecular N—H...O hydrogen bond.
Karim Chkirate, Joel T. Mague, Nada Kheira Sebbar, Younes Ouzidan, El Mokhtar Essassi   +4 more
doaj   +1 more source

Experimental and Theoretical Tests on the Corrosion Protection of Mild Steel in Hydrochloric Acid Environment by the Use of Pyrazole Derivative. [PDF]

Materials (Basel), 2023
Boudalia M, Fernández-Domene RM, Guo L, Echihi S, Belghiti ME, Zarrouk A, Zarrouk A, Bellaouchou A, Guenbour A, García-Antón J.   +9 more
europepmc   +1 more source

BORAZANs:  Tunable Fluorophores Based on 2-(Pyrazolyl)aniline Chelates of Diphenylboron [PDF]

, 2007
The reaction between 2-pyrazolyl-4-X-anilines, H(pzAnX), (X = para-OMe (L1), Me (L2), H (L3), Cl (L4), CO2Et (L5), CF3 (L6), CN (L7)) and triphenylboron in boiling toluene affords the respective, highly emissive N,N‘-boron chelate complexes, BPh2(pzAnX) (
Gardinier, James R., Liddle, Brendan J., Lindeman, Sergey V., Macedo, Felipe P., Morin, Tyler James, Shukla, Ruchi, Silva, Rosalice M.   +6 more
core   +1 more source

Synthesis and Reactivity of 3‐Aminosydnones in Cycloaddition Reactions With Alkynes

Chemistry – A European Journal, EarlyView.
The synthesis, functionalization, and reactivity as dipoles of 3‐aminosydnones have been investigated. These neglected compounds undergo smooth cycloaddition reactions with strained alkynes, leading to 1‐aminopyrazoles. ABSTRACT We present in this article the synthesis, functionalization, and properties of 3‐aminosydnones, a forgotten class of ...
Apolline Dominic, Timothée D'anfray, Guillaume Force, David‐Alexandre Buisson, Maxime Tricoire, Alexis Leblais, Davide Audisio, Frédéric Taran   +7 more
wiley   +1 more source

Synthesis of Tricyclic Condensed Rings Incorporating the Pyrazole or Isoxazole Moieties Bonded to a 4-Piperidinyl Substituent

Molecules, 2013
In this paper we report the synthesis of new compounds based on the pyrazole and isoxazole framework fused to a cycloalkene unit, and bearing as a substituent the 1-piperidinyl group as new examples of potential antipsychotic molecules.
Giorgio Chelucci, Gérard A. Pinna, Giovanni Loriga, Giansalvo Pinna   +3 more
doaj   +1 more source