Results 91 to 100 of about 15,779 (274)

Enzymatic Transglycosylation Features in Synthesis of 8-Aza-7-Deazapurine Fleximer Nucleosides by Recombinant E. coli PNP: Synthesis and Structure Determination of Minor Products

Biomolecules
Enzymatic transglycosylation of the fleximer base 4-(4-aminopyridine-3-yl)-1H-pyrazole using recombinant E. coli purine nucleoside phosphorylase (PNP) resulted in the formation of “non-typical” minor products of the reaction.
Barbara Z. Eletskaya, Anton F. Mironov, Ilya V. Fateev, Maria Ya. Berzina, Konstantin V. Antonov, Olga S. Smirnova, Alexandra B. Zatsepina, Alexandra O. Arnautova, Yulia A. Abramchik, Alexander S. Paramonov, Alexey L. Kayushin, Anastasia L. Khandazhinskaya, Elena S. Matyugina, Sergey N. Kochetkov, Anatoly I. Miroshnikov, Igor A. Mikhailopulo, Roman S. Esipov, Irina D. Konstantinova   +17 more
doaj   +1 more source

Cytotoxicity study of pyrazole derivatives

Bangladesh Journal of Pharmacology, 2008
El compuesto heterocíclico de pirazolona, 3-metil-1-fenil-2-pirazolina-5-ona 2(a) se sintetizó mediante reacción de condensación entre acetoacetato de etilo y fenilhidrazina y se convirtió en sus derivados heterocíclicos correspondientes 2(b) a 2(f2) .
Nusrat Binta Ahasan, Rabiul Islam
openaire   +3 more sources

Redox‐Active Bisphosphines Based on a W(II)‐Propargyl Complex Backbone

European Journal of Inorganic Chemistry, EarlyView.
Three bisphosphine ligands based on tungsten(II) propargyl‐type alkyne complexes were synthesized and characterized. The methanolate derivative was used as a metalla‐ligand for the preparation of a binuclear bisphosphine‐κ2‐PdCl2 complex. In both cases, IR spectroelectrochemistry (IR‐SEC) measurements revealed a successive process following oxidation ...
Friederike M. Hamann, Dirk Michalik, Martina Beese, Anke Spannenberg, Alexander Villinger, Klaus Neymeyr, Robert Francke, Wolfram W. Seidel   +7 more
wiley   +1 more source

New Potent 5α- Reductase and Aromatase Inhibitors Derived from 1,2,3-Triazole Derivative

Molecules, 2020
This work describes the utility of pyrazole-4-carbaldehyde 1 as starting material for the synthesis of a novel potent series of 5α-reductase and aromatase inhibitors derived from 1,2,3-triazole derivative. Condensation of 1 with active methylene and
Mohamed El-Naggar, Amira S. Abd El-All, Shweekar I. A. El-Naem, Mohamed M. Abdalla, Huda R. M. Rashdan   +4 more
doaj   +1 more source

Correlation Between the Molecular Structure of Metal‐Supporting Ligands and Catalysis in the Oxygenase‐Mimicking Immobilized Metal Complex Catalysts

European Journal of Inorganic Chemistry, Volume 29, Issue 16, 4 June 2026.
The correlation between the structures of metal complexes immobilized in the mesopores of hydrophobically modified silicate supports was examined in relation to the catalytic activities toward C‐H oxidation. On the alkene oxidation with H2O2, the iron catalyst bearing bis(imidazolyl)methane ligand promotes allylic oxidation, whereas the mononuclear ...
Yuta Akizawa, Hiroe Fukuzaki, Nana Aizawa, Sho Ikeda, Airi Kawabe, Saori Nishiyama, Iori Nagasawa, Masaya Okamura, Shiro Hikichi   +8 more
wiley   +1 more source

BORAZANs:  Tunable Fluorophores Based on 2-(Pyrazolyl)aniline Chelates of Diphenylboron [PDF]

, 2007
The reaction between 2-pyrazolyl-4-X-anilines, H(pzAnX), (X = para-OMe (L1), Me (L2), H (L3), Cl (L4), CO2Et (L5), CF3 (L6), CN (L7)) and triphenylboron in boiling toluene affords the respective, highly emissive N,N‘-boron chelate complexes, BPh2(pzAnX) (
Gardinier, James R., Liddle, Brendan J., Lindeman, Sergey V., Macedo, Felipe P., Morin, Tyler James, Shukla, Ruchi, Silva, Rosalice M.   +6 more
core   +1 more source

Rhodium(I)-N-heterocyclic carbene catalyst for selective coupling of N-vinylpyrazoles with alkynes via C-H activation [PDF]

, 2016
The complex [Rh(μ-Cl)(IPr)(η2-coe)]2 {IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-carbene, coe = cis-cyclooctene} efficiently catalyzes the coupling of alkynes and N-vinylpyrazole via C–H activation, leading to Markovnikov-selective butadienylpyrazole
Azpíroz, Ramón, Castarlenas, Ricardo, Giuseppe, Andrea di, Lahoz, Fernando J., Oro, Luis A., Passarelli, Vincenzo, Pérez-Torrente, Jesús J., Rubio-Pérez, Laura   +7 more
core   +1 more source

Bridging Stability and Reactivity: Novel Dinucleating Ligand With Rigid Backbone Stabilizes a Cu2O2 Side‐On Peroxido Structure

European Journal of Inorganic Chemistry, EarlyView.
The herein‐developed tyrosinase model complex enables the transfer of tyrosinase‐like catalytic oxygenation activity into artificial systems. Therefore, it enables the use of molecular oxygen for oxygenation and oxidation of phenolic substrates at room temperature.
Rosalie Dalhoff, Christine Charlotte Müller, Alexander Hoffmann, Sonja Herres‐Pawlis   +3 more
wiley   +1 more source

Comparative studies of the Pschorr reaction in the pyrazole series. Access to the new dibenzo(e,g)pyrazolo(1,5-a)(1,3)diazocine system of pharmaceutical interest [PDF]

, 2008
The diazonium tetrafluoroborate 11 obtained from 2-amino-N-methyl-N-(1-phenyl-3-methylpyrazol-5-yl)benzamide was transformed in dry acetonitrile via an ionic or radical pathway. Diferences were observed with respect to ionic or radical transformations in
BOMBIERI, G, CASCIOFERRO, Stella Maria, DAIDONE, Giuseppe, MAGGIO, Benedetta, MENEGHETTI, F, PLESCIA, Salvatore, RAFFA, Demetrio, RAIMONDI, Maria Valeria, SABATINO, Maria Antonietta   +8 more
core   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source