Results 181 to 190 of about 38,574 (278)

The synthesis and investigation of novel 3-benzoylbenzofurans and pyrazole derivatives for anti-HIV activity. [PDF]

RSC Med Chem
Khuzwayo SS, Selepe MA, Meyer D, Gama NH.   +3 more
europepmc   +1 more source

Synthetic Inhibitors of Alcohol Dehydrogenase. Pyrazoles Containing an Unsaturated Hydrocarbon Residue in the 4-Position. [PDF]

, 1982
Bo‐Ragnar Tolf, Richard Dahlbom, Hugo Theorell, Åke Åkeson, Curt R. Enzell, Jan-Eric Berg, Kurt Torssell   +6 more
openalex   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Privileged Chiral Photocatalysts

Angewandte Chemie, Volume 137, Issue 36, September 1, 2025.
Privileged chiral catalysts have transformed asymmetric synthesis, conferring generality to processes that are routinely leveraged in the construction of societally important functional small molecules. This mini‐review is intended to survey the conception and evolution of privileged chiral photocatalyst scaffolds that enable simultaneous orchestration
Emanuel Studer, Smita Mandal, Timo Stünkel, Ryan Gilmour   +3 more
wiley   +2 more sources

Antifungal activity and biocompatibility assessment with molecular docking and dynamic simulations of new pyrazole derivatives. [PDF]

BMC Biotechnol
Abd-Elhalim BT, El-Bana GG, El-Sayed AF, Abdel-Ghani GE.   +3 more
europepmc   +1 more source

Effect of pH on Pyrazole Binding to Liver Alcohol Dehydrogenase [PDF]

, 1981
Pia Andersson, Jan KVASSMAN, Anders Lindström, Bertil OLDÉN, Gösta Pettersson   +4 more
openalex   +1 more source

Elucidating the Role and Mechanism of Alpha‐Enolase in Senescent Amelioration via Metabolic Reprogramming

Cell Proliferation, EarlyView.
KB2764 interacted with alpha‐enolase (ENO1) and pyruvate kinase M (PKM), ultimately leading to PKM phosphorylation of ENO1. KB2764 consequently increased mitochondrial ATP production and decreased glycolysis dependence. Furthermore, the action of KB2764 extends its application to extend the lifespan of Caenorhabditis elegans.
Yun Haeng Lee, Hyunwoong Lim, Gyungmin Kim, Geonhee Jang, Myeong Uk Kuk, Ji Ho Park, Jee hee Yoon, Yoo Jin Lee, Duyeol Kim, Byeonghyeon So, Minseon Kim, Hyung Wook Kwon, Youngjoo Byun, Joon Tae Park   +13 more
wiley   +1 more source

Recent highlights in the synthesis and biological significance of pyrazole derivatives. [PDF]

Heliyon
Moussa Z, Ramanathan M, Alharmoozi SM, Alkaabi SAS, Al Aryani SHM, Ahmed SA, Al-Masri HT.   +6 more
europepmc   +1 more source

APPi: A Multiscale Qualitative–Quantitative Insecticide‐Likeness Evaluation Platform and Application

Plant Biotechnology Journal, EarlyView.
An Agrochem Predictive Platform for Insecticide‐likeness: From Qualitative Rules to Quantitative Modeling and Visualization. ABSTRACT According to the Food and Agriculture Organization of the United Nations (FAO), pests reduce global crop production by 14% annually. The growing challenge of pest resistance, coupled with the relatively low success rates
Jia‐lin Cui, Qi He, Bin‐yan Jin, Xin‐peng Sun, Hua Li, Yue Wei, Xiao‐ming Zhang, Li Zhang   +7 more
wiley   +1 more source

1,2-Dihydropyrimidine synthesis <i>via</i> titanium-mediated multicomponent coupling of alkynes, nitriles, and aldehydes. [PDF]

Chem Commun (Camb)
Dunscomb RJ, Frye CW, Murray X, Tonks IA.   +3 more
europepmc   +1 more source