Results 21 to 30 of about 1,851 (175)
Speciation‐Controlled C–F Bond Functionalization Enabled by Zwitterionic Pnictinidenes
Angewandte Chemie, EarlyView.Zwitterionic pnictinidenes turn C–F activation into C–X bond construction, enabling broad defluorinative functionalization of polyfluoro(hetero)arenes under mild conditions. Rather than following a metallomimetic Sb(I)/Sb(III) redox turnover, catalysis is redirected by ligand scrambling into a redox‐neutral manifold, revealing catalyst speciation as a ...
Irene Sánchez‐Sordo +4 more
wiley +2 more sources
Novel Ring Systems: Spiro[Cycloalkane] Derivatives of Triazolo- and Tetrazolo-Pyridazines
Molecules, 2021 In orderto synthesize new pyridazine derivatives anellated with different nitrogen heterocyclic moieties, spiro[cycloalkane]pyridazinones were transformed into the corresponding thioxo derivatives via a reaction with phosphorus pentasulfide. The reaction
Csilla Sepsey Für +6 more
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International Journal of Electrochemical Science, 2020 The present study theoretically investigates the molecular properties of two pyridazine derivatives (5-benzyl-6-methyl pyridazine-3-one, PO and 5-benzyl-6-methyl pyridazine-3-thione, PS) using quantum chemical technique (Parameterization Method 3). It is
Ubong Eduok
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Molecules, 2013 Aiming for the synthesis of new heterocyclic compounds containing a sulfonamido moiety suitable for use as antibacterial agents, the precursor ethyl {[4-N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenylazo}cyanoacetate was reacted with a variety of active ...
Eman A. El-Bordany +2 more
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Alzheimer’s Research & Therapy, 2019 Background The lack of effective treatment options for Alzheimer’s disease (AD) is of momentous societal concern. Synaptic loss is the hallmark of AD that correlates best with impaired memory and occurs early in the disease process, before the onset of ...
Joshua B. Foster +9 more
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Study on the Acid⁃Catalyzed Cyclization Reaction of Allylbenzenes and Tetrazine
Shiyou huagong gaodeng xuexiao xuebaoIndeno[1,2⁃d]pyridazine derivatives have wide applications in pesticides,pharmaceuticals,and other fields due to their excellent biological activities.Therefore,the development of rapid and efficient synthetic methods for these compounds has attracted ...
Wenqing LIU, He WANG, Xin WANG, Lei LI
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Bis-Pyridazine Derivatives with Anticancer Activity
Proceedings, 2019 Over the last decades, pyridazine derivatives are considered “privileged structures” in medicinal chemistry, with special attention being given to pyridazinones derivatives, which were found to have a large range of biological activities ...
Amariucai-Mantu Dorina +3 more
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Synthesis of New Compounds From Pyridazine Derivatives, and Preliminary Pharmacological Study
مجلة بغداد للعلومThere has been an increasing interest in the chemistry of pyridazine derivatives because of their biological significance. Pyridazine has been reported to possess variety of biological activities like antidiabetic, anticancer, anti-AIDS, anti ...
Mohammed Hasan AL-Dahlaki +1 more
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An expedient and new synthesis of pyrrolo[1,2-b]pyridazine derivatives
Beilstein Journal of Organic Chemistry, 2009 The reaction of 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-pentanoic acid phenylamide with tertiary butyl carbazate and subsequent condensation of the resulting carbamate derivative with a chalcone provided a facile new approach to pyrrolo[
Rajeshwar Reddy Sagyam +5 more
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Synthesis and Antifungal Activity of 5-Chloro-6-Phenylpyridazin-3(2H)-one Derivatives
Molecules, 2009 An effective method has been developed for the preparation under mild conditions of novel pyridazine derivatives from the easily accessible starting materials mucochloric acid and benzene.
Deyu Hu +4 more
doaj +1 more source