Results 41 to 50 of about 2,698 (209)

Pyridazinone Compounds: A Mini review on their antifungal activities

open access: yesInternational Journal of New Chemistry, 2020
Pyridazine derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activity. They are widely used in pharmaceuticals and agrochemicals.
Mohammad Asif Abida , Md Tauquir Alam
doaj   +1 more source

2-Methyl-6-(4-aminophenyl)-4,5-dihydro-3(2H)-pyridazinone Synthon for Some New Annelated 1,2,3-Selena/Thiadiazoles and 2H-Diazaphospholes with Anticipated Biological Activity and Quantum Chemical Calculations

open access: yesMolecules, 2023
A convenient and efficient synthetic protocol for the new selenadiazole. Thiadiazole and diazaphosphole derivatives incorporating a pyridazine moiety originating from 4-(4-aminophenyl)-4-oxobutanoic acid (1) were described.
I. E. El-Shamy   +4 more
doaj   +1 more source

Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects

open access: yesAdvanced Science, EarlyView.
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu   +7 more
wiley   +1 more source

Diverse chemical and biological potentials of various pyridazine and pyridazinone derivatives

open access: yes, 2019
A series of heterocyclic compounds incorporating pyridazine moiety were for diverse biological activities. Pyridazines and pyridazinones derivatives showed wide spectrum of biological activities such as vasodialator, cardiotonic, anticonvulsant ...
Md. Tauquir Alam, Mohammad Asif, Abida
core   +1 more source

Formal [4 + 2] combined ionic and radical approach of vinylogous enaminonitriles to access highly substituted sulfonyl pyridazines

open access: yesCommunications Chemistry
Pyridazine derivatives hold significant interest due to their broad applications in pharmaceuticals and materials science, where they serve as valuable scaffolds for bioactive compounds and functional materials.
Chanhyun Jung   +10 more
doaj   +1 more source

Synthesis of 6-Alkynylated Purine-Containing DNA via On-Column Sonogashira Coupling and Investigation of Their Base-Pairing Properties

open access: yesMolecules, 2023
Synthetic unnatural base pairs have been proven to be attractive tools for the development of DNA-based biotechnology. Our group has very recently reported on alkynylated purine–pyridazine pairs, which exhibit selective and stable base-pairing via ...
Hidenori Okamura   +4 more
doaj   +1 more source

Strategy for the Synthesis of Pyridazine Heterocycles and Their Derivatives

open access: yes, 2016
The first synthesis of novel fused pyridazines has been realized starting from 1,3-diketones involving a Diaza–Wittig reaction as a key step. A convenient strategy was elaborated to access versatile pyridazine derivatives allowing the variation of ...
Oscar Mammoliti (1923286)   +4 more
core   +1 more source

Unlocking Catalyst Activation as a Critical Bottleneck in Cross‐Coupling Reactions: Room‐Temperature Couplings of Weak Nucleophiles Enabled by [Pd(1‐MeNAP)TFA]2 Precatalysts

open access: yesAngewandte Chemie International Edition, EarlyView.
In many Pd‐catalyzed cross‐couplings, catalyst performance has been found to be limited by catalyst activation. Methylnaphthyl (MeNAP) palladium trifluoroacetate dimers are presented as easy‐to‐store and easy‐to‐handle precursors, which rapidly activate under reaction conditions, even when only weakly coordinating, non‐reducing nucleophiles are present.
Sourav Manna   +6 more
wiley   +1 more source

Synthesis and biological evaluation of novel pyridazine analogues (3-aldehyde-1-phenylpyridazine derivatives)

open access: yes, 2010
Five new pyridazine compounds were synthesized. The usefulness of IR, 1HNMR and 13CNMR spectroscopy for the structural analysis of the new compounds is well established.
Odin, E.M   +3 more
core   +1 more source

Study On Synthesis and Biological Activity of Some Pyridopyridazine Derivatives

open access: yesActa Chimica Slovenica, 2018
In this study, new pyrido[3,4-d]pyridazine derivatives were synthesized and evaluated for their in vitro antibacterial, antifungal and antimycobacterial activities.
Sevilay Akçay   +3 more
doaj   +1 more source

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