Results 51 to 60 of about 1,851 (175)

New thiazol-pyridazine derivatives as antimicrobial and antiviral candidates: Synthesis, and application

Journal of Saudi Chemical Society
In this manuscript, we are motivated to investigate the reaction site-selectivity for the hydrazo thiazole derivatives (6a–c) with different types of active methylene groups such as malononitrile, and ethyl cyanoacetate.
Fuad A. Alatawi, Abdulmajeed F. Alrefaei, Alaa M. Alqahtani, Amerah Alsoliemy, Hanadi A. Katouah, Hana M. Abumelha, Fawaz A. Saad, Nashwa M. El-Metwaly   +7 more
doaj   +1 more source

Electrochemical and Spectroscopic Studies of Pyridazine Derivatives

Portugaliae Electrochimica Acta, 2004
This work reports on cyclic voltammetry and spectroscopic UV-Vis investigations of some pyridazine derivatives 1-8 in dimethylformamide. In the electrochemical study, monochlorinated pyridazines 2-8 exhibit two reductions but in the case of dichlorinated derivative 1 an additional wave is seen for the reduction of the second carbon-chloride bond.
Vieira,L.M.C., Fonseca,A.M., Raposo,M.M.M., Kirsch,G.   +3 more
openaire   +3 more sources

Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy

Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.
Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez, Robby Büchner, Mattis Fondell, Albert M. Brouwer   +3 more
wiley   +1 more source

3,6-Dibromopyridazine-4,5-diamine

Molbank, 2019
Dihalogenated derivatives of 1,2,5-chalcogenadiazoles fused with benzene or heterocyclic rings are of interest as starting compounds for photovoltaic materials.
Timofey N. Chmovzh, Ekaterina A. Knyazeva, Olga O. Ustimenko, Oleg A. Rakitin   +3 more
doaj   +1 more source

Straightforward Synthesis, Spectroscopic Characterizations, Molecular Docking, Molecular Dynamics Simulations, and Comprehensive DFT Calculations of Novel Tetrazole 1,5 and 2,5‐Disubstituted Tetrazole Scaffolds

ChemistryOpen, Volume 15, Issue 8, August 2026.
A series of novel 1,5‐ and 2,5‐disubstituted tetrazole heterocyclic scaffolds was synthesized and characterized by single‐crystal X‐ray diffraction. Their electronic properties were investigated using density functional theory calculations, while molecular docking and molecular dynamics simulations revealed promising biological potential and favorable ...
Riham Sghyar, Ahmed Chelouan, Brahim El Ibrahimi, Olivier Blacque, Basavarajaiah Suliphuldevara Mathada, Prashantha Karunakar, Oussama Moussaoui, Mouad Lahyaoui, Joel T. Mague, Ali Aghmiz, Manal El‐Gendy, Mohamed Hefnawy, Nada Kheira Sebbar   +12 more
wiley   +1 more source

Supramolecular Surface Functionalization of Single‐Walled Carbon Nanotubes With Conjugated Graft Copolymers

Journal of Polymer Science, Volume 64, Issue 15, Page 3310-3320, 1 August 2026.
Post‐polymerization modification of poly(tetrazine‐co‐fluorene) conjugated polymer via an inverse‐electron‐demand Diels‐Alder reaction (IEDDA) introduces hydroxyl initiators that enable surface‐initiated ring‐opening polymerization (ROP) of lactide.
Shagana Kukendran, Alex Adronov
wiley   +1 more source

Microwave Assisted Condensation Reactions of 2-Aryl Hydrazonopropanals with Nucleophilic Reagents and Dimethyl Acetylenedicarboxylate

Molecules, 2007
The reaction of methyl ketones 1a-g with dimethylformamide dimethylacetal (DMFDMA) afforded the enaminones 2a-g, which were coupled with diazotized aromatic amines 3a,b to give the corresponding aryl hydrazones 6a-h.
Rita M. Borik, Khadijah M. Al-Zaydi
doaj   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source

Oligonucleotides Post‐Synthetic Modifications: An Overview of Clickable Nucleoside Phosphoramidites Suitable for Solid‐Phase Synthesis

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Clickable nucleoside phosphoramidites can be incorporated into oligonucleotides via solid‐phase synthesis (SPOS), enabling rapid and site‐specific post‐functionalization using bioorthogonal reactions. This review highlights their design, synthetic accessibility, and SPOS incorporation requirements, along with the kinetics and efficiency of post ...
Sébastien Depienne, Alexandra Bristiel, Dominique Urban, Dominique Guianvarc’h   +3 more
wiley   +1 more source