Results 21 to 30 of about 10,045 (252)

Syntheses and Applications of 1,2,3-Triazole-Fused Pyrazines and Pyridazines

open access: yesMolecules, 2022
Pyrazines and pyridazines fused to 1,2,3-triazoles comprise a set of heterocycles obtained through a variety of synthetic routes. Two typical modes of constructing these heterocyclic ring systems are cyclizing a heterocyclic diamine with a nitrite or ...
Gavin R. Hoffman, Allen M. Schoffstall
doaj   +1 more source

Heterocyclic synthesis with nitriles: synthesis of pyridazine and pyridopyridazine derivatives [PDF]

open access: yes, 2007
The reaction of MND with aryldiazonium chlorides followed by cyclization afforded the pyridazinimine derivatives. Reaction of the latter with another mole of malononitrile produce only pyrido[3,2-c]pyridazine derivatives.
Campos, Ana M. F. Oliveira   +2 more
core   +1 more source

Design, synthesis and characterization of novel thienylpyridazine derivatives for optical applications [PDF]

open access: yes, 2015
We report in this work the synthesis and the photophysical characterization of novel pyridazine derivatives, functionalized in position 3, with different (hetero)aromatic groups (indole, cyanophenyl, nitrophenyl).
Fernandes, Sara S. M.   +1 more
core   +3 more sources

Single crystal X-ray structure of 3-amino-5-(4-chlorophenyl)pyridazine-4-carbonitrile [PDF]

open access: yes, 2013
The title compound 3-amino-5-(4-chlorophenyl)pyridazine-4-carbonitrile was prepared by a one-pot three-component reaction of malononitrile with corresponding arylglyoxal in the presence of hydrazine hydrate at room temperature in water and ethanol.
Ahmad Poursattar Marjani   +3 more
core   +1 more source

Synthesis and Antibacterial Evaluation of Novel Heterocyclic Compounds Containing a Sulfonamido Moiety

open access: yesMolecules, 2013
Aiming for the synthesis of new heterocyclic compounds containing a sulfonamido moiety suitable for use as antibacterial agents, the precursor ethyl {[4-N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenylazo}cyanoacetate was reacted with a variety of active ...
Eman A. El-Bordany   +2 more
doaj   +1 more source

Multi Component Reactions under Increased Pressure: On the Mechanism of Formation of Pyridazino[5,4,3-de][1,6]naphthyridine Derivatives by the Reaction of Malononitrile, Aldehydes and 2-Oxoglyoxalarylhydrazones in Q-Tubes

open access: yesMolecules, 2017
Efficient synthesis of phenanthridin-6(5H)-one derivatives 12a–n in a four-component reaction of aldehyde hydrazone, aromatic aldehydes and malononitrile in Q-Tubes is reported. The results showed that the methodology has the advantage of being a one-pot
Majdah A. AL-Johani   +5 more
doaj   +1 more source

Pyridazinone Compounds: A Mini review on their antifungal activities

open access: yesInternational Journal of New Chemistry, 2020
Pyridazine derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activity. They are widely used in pharmaceuticals and agrochemicals.
Mohammad Asif Abida , Md Tauquir Alam
doaj   +1 more source

Functionalization of diazines and benzo derivatives through deprotonated intermediates. [PDF]

open access: yes, 2008
International audienceThis critical review targets as a readership researchers generally oriented toward organic synthesis and in particular those active in heterocyclic chemistry.
Chevallier, Floris, Mongin, Florence
core   +2 more sources

Reactions with Hydrazonoyl Halides. 31. Synthesis of Some New Pyrrolidino[3,4-c]pyrazolines, Pyrazoles, and Pyrazolo[3,4-d]pyridazines

open access: yesMolecules, 2000
Pyrrolidino[3,4-c]pyrazoline and pyrazole derivatives were synthesized via reactions of a substituted hydrazonoyl bromide with N-arylmaleimides and active methylene reagents, respectively. Synthesized pyrazoles were reacted with hydrazine hydrate to give
Nagla A. Ahmed   +3 more
doaj   +1 more source

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