Results 61 to 70 of about 10,045 (252)

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Synthesis and quantitative structure–activity relationship study of substituted imidazophosphor ester based tetrazolo[1,5-b]pyridazines as antinociceptive/anti-inflammatory agents

Beilstein Journal of Organic Chemistry, 2013
A high-yielding general synthesis of imidazophosphor ester based tetrazolo[1,5-b]pyridazines is described. A conjugated reaction between 3,6-diazidopyridazine and different types of phosphonyl carbanion reagents followed by intramolecular cyclization ...
Wafaa M. Abdou, Neven A. Ganoub, Eman Sabry   +2 more
doaj   +1 more source

Novel heterocyclic hybrids of pyrazole targeting dihydrofolate reductase: design, biological evaluation and in silico studies

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
A novel series of pyrazole analogues including hydrazones, pyrazolo[4,3-c]-pyridazines, pyrazolo[3,4-e][1,2,4]triazine and pyrazolo[3,4-d][1,2,3]triazoles was designed, synthesised and screened for their in vitro antimicrobial and DHFR inhibition ...
Ismail M. M. Othman, Mohamed A. M. Gad-Elkareem, Abd El-Galil E. Amr, Mohamed A. Al-Omar, Eman S. Nossier, Elsayed A. Elsayed   +5 more
doaj   +1 more source

Synthesis and Characterization of some Thallium Salt Complexes [PDF]

, 2014
Research into conductive organic and organometallic polymers began in 1977 when Heeger, Macdiarmid, and Shirakawa first doped polyacteylene with Iodine.
Dopierala, Levi
core   +1 more source

π‐Expanded Nitrogen‐Cation (N+)‐Doped Polycyclic Aromatic Hydrocarbons: A Review of Intramolecular Cyclization Routes to Benzo[c]Quinolizinium, Triazinium, Pyridoquinazolinium, and Pyridoquinoxalinium Frameworks

European Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
This review surveys recent progress in the synthesis of extended aromatic quinolizinium derivatives via intramolecular SNAr and oxidative 6π‐electrocyclization. Conventional thermal approaches are discussed alongside emerging, sustainable activation methods such as electrosynthesis and photochemical processes.
Marine Labro, Cyrille Monnereau, Laure Guy   +2 more
wiley   +1 more source

π-Bond Screening in Benzonorbornadienes: The Role of 7-Substituents in Governing the Facial Selectivity for the Diels-Alder Reaction of Benzonorbornadienes with 3,6-Di(2-pyridyl)-s-Tetrazine

Molecules, 2001
Benzonorbornadiene 21, 7-spirocyclopropylbenzonorbornadiene 23, 7,7-dimethylbenzonorbornadiene 25, and 7-spirocyclopentylbenzonorbornadiene 27 have been reacted with 3,6-di(2-pyridyl)-s-tetrazine (rate: 21>23>25=27) to form symmetrical 4,5 ...
Peter A. Harrison, Ronald N. Warrener
doaj   +1 more source

4,4′-([1,2,5]Thiadiazolo[3,4-d]pyridazine-4,7-diyl)bis(N,N-bis(4-methoxyphenyl)aniline)

Molbank, 2022
Donor-acceptor-dyes with extended conjugation, such as D–π–A–π–D type, are being intensively investigated as components of near-infrared (NIR) organic light-emitting diodes (OLEDs). In this communication, novel D–π–A–π–D dye, 4,4′-([1,2,5]thiadiazolo[3,4-
Timofey N. Chmovzh, Timofey A. Kudryashev, Oleg A. Rakitin   +2 more
doaj   +1 more source

Small Molecules in Development for the Treatment of Spinal Muscular Atrophy [PDF]

, 2016
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease resulting from pathologically low levels of survival motor neuron (SMN) protein.
Androphy, Elliot J., Calder, Alyssa N., Hodgetts, Kevin J.   +2 more
core   +1 more source

RNA‐Lebendzellmikroskopie via click‐funktionalisierter TriPPPro Nucleotid‐Reporter

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die intrazelluläre Zufuhr von trans‐Cycloocten und Bicyclo[6.1.0]nonin als sterisch anspruchsvolle Gruppen für die Diels–Alder‐Reaktion mit inversem Elektronenbedarf wurde durch die Triphosphat‐Prodrug‐Strategie (TriPPPro) erreicht. Nach der Hydrolyse innerhalb der Zelle werden die modifizierten Uridine und Cytidine metabolisch in die neu entstehende ...
J. Iven H. Knaack, Eileen List, Dörte Stalling, Vincente T. Sterrenberg, Chris Meier, Hans‐Achim Wagenknecht, Jens B. Bosse   +6 more
wiley   +1 more source

Glycerol and Q-Tubes: Green Catalyst and Technique for Synthesis of Polyfunctionally Substituted Heteroaromatics and Anilines

Molecules, 2019
The role of glycerol as a green bio-based solvent, reactant, and/or a catalyst in the synthesis of novel heterocycles, under pressure, is studied. Synthesis of novel quinolines in good yields using a new modified Skraup synthesis, utilizing glycerol and ...
Douaa Salman AlMarzouq, Noha M. Hilmy Elnagdi   +1 more
doaj   +1 more source