Results 11 to 20 of about 8,502 (208)
Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds [PDF]
Hemijska Industrija, 2014 2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications.
Mijin Dušan Ž. +3 more
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Synthesis of New Aza-Heterocyclic Based on 2-Pyridone
Chemistry ProceedingsIn this work, we present new methods of synthesis of different molecules including a 2-pyridone nucleus. First, we prepared a series of 1H-free 2-pyridones and N-alkyl 2-pyridones from ethyl cyanoacetate, aromatic aldehydes, various acetophenone ...
Ikram Baba-Ahmed +4 more
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catena-Poly[[[(2-pyridone-κO)silver(I)]-μ-2-pyridone-κ2O:O] hexafluoridophosphate]
Acta Crystallographica Section E, 2010 The asymmetric unit of the polymeric title salt, {[Ag(C5H5NO)2]PF6}n, comprises an AgI cation (located on a twofold axis), two 2-pyridone ligands (with distinct coordination modes), and half a PF6− anion (situated on a centre of inversion). The
Edward R. T. Tiekink +2 more
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Acta Crystallographica Section E, 2011 The crystal structure of the title compound, C6H7NO, is stabilized by intermolecular N—H...O hydrogen bonds, resulting in inversion dimers. The structure is further consolidated by weak C—H...O hydrogen bonds.
Shulin Mao, Luo Yanghui, Pan Meiling
doaj +3 more sources
, 2018 In this thesis, the synthesis and coordination chemistry of a series of novel NNN and NN proton responsive ligands are described. All the ligands and complexes have been characterized by a combination of multinuclear NMR spectroscopic techniques, mass ...
Mona Hanash A. Alhalafi (7716149)
core +7 more sources
Synthesis, Structure, and Hydroboration Reactivity of Anionic Nickel(0) Complexes Supported by Bidentate NHC-Pyridone Ligands [PDF]
, 2022 A family of anionic, formally nickel(0) complexes supported by bidentate NHC–pyridone ligands is described. The unsymmetric chelating environment and capping [K(18-crown-6)]+ countercation allow isolation of single-component, monometallic complexes in ...
C. Rose, Kennedy +4 more
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2-Pyridone-assisted palladium-catalyzed regioselective arylation of naphthamides. [PDF]
RSC AdvThe 2-pyridone scaffold receives attention in medicinal chemistry due to its bioisostere properties, which significantly contributing to lipophilicity, solubility, metabolic stability, and drug off-target effects.
Prajapati J, Chatterjee S.
europepmc +2 more sources
Avoiding pitfalls when modelling ligands in macromolecular crystallography. [PDF]
Acta Crystallogr D Struct BiolFlawed protein–ligand X‐ray structures can misdirect drug discovery based on PDB‐deposited models. This review uses publicly available PDB examples to highlight potential pitfalls, from absent ligands to incorrect chemistry, and presents a practical validation approach to improve model reliability.The determination of protein–ligand complex structures ...
Smart OS +4 more
europepmc +2 more sources
Excitation Energy-Dependent Decay Dynamics of the S1 State of N‑Methyl-2-pyridone
, 2023 The UV-induced decay dynamics of N-methyl-2-pyridone is investigated using a femtosecond time-resolved photoelectron spectroscopy method. Irradiation in the wavelength range of 339.3–258.9 nm prepares N-methyl-2-pyridone molecules with very different ...
Dongyuan Yang (8968340) +5 more
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Enzymatic synthesis of vitamin B6 precursor [PDF]
Journal of the Serbian Chemical Society, 2013 3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Prlainović Nevena Ž. +4 more
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