Results 21 to 30 of about 8,502 (208)

One-Pot Two-Step Catalytic Synthesis of Rationally Designed 6-amino-2-pyridone-3,5-dicarbonitriles Enabling Anti-Cancer Bioactivity [PDF]

, 2022
Herein we report a one-pot two-step synthesis of a bioactive 6-amino-2-pyridone-3,5-dicarbonitrile derivative using natural product catalysts betaine and guanidine carbonate.
Dipti B, Upadhyay, Joaquina, Nogales, Ruturajsinh M, Vala, Celestine, Chi, Lynden G, Nicely, Hitendra M , Patel, Sourav, Banerjee   +6 more
core   +1 more source

Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds

Journal of Saudi Chemical Society, 2021
Background: The chemistry and applications of 2-pyridone structures have recently attracted a lot of attention due to their uses as synthetic intermediates and their biological importance.
Mostafa M.K. Amer, Maged A. Aziz, Wesam S. Shehab, Magda H. Abdellattif, Samar M. Mouneir   +4 more
doaj   +1 more source

Synthesis of 4-Pyridone-3-sulfate and an improved synthesis of 3-Hydroxy-4-Pyridone

Chemistry Central Journal, 2009
An improved synthesis of 3-hydroxy-4-pyridone via an Elbs oxidation of 4-pyridone and isolation of 4-pyridone-3-sulfate is described.
Behrman Edward J
doaj   +1 more source

Structure-Dependent Electrochemical Behavior of 2-Pyridone Derivatives: A Combined Experimental and Theoretical Study

Applied Sciences, 2023
In this work, the electrooxidation ability of nine pyridones was evaluated using cyclic (CV) and square-wave voltammetry (SWV) in Britton–Robinson (BR) aqueous buffer solutions on a glassy carbon electrode (GC). The dependence of electrochemical activity
Aleksandra Mašulović, Jelena D. Lović, Jelena Lađarević, Vesna Vitnik, Željko Vitnik, Milka Avramov Ivić, Dušan Mijin   +6 more
doaj   +1 more source

One-pot multicomponent green synthesis of novel series of 4-hydroxy-2-pyridone-fused spiropyrans catalyzed by acetic acid

, 2023
An efficient one-pot multicomponent reaction is reported for synthesizing a novel series 4-hydroxy-2-pyridone-fused spiropyran through the reaction of 4-hydroxy-6-methylpyridine-2-ones alkaloids, malononitrile or ethyl cyanoacetate, and ninhydrin or ...
Mahmood Kamali (16489191), Asadollah Ebrahimi (16489194)   +1 more
core   +1 more source

Investigation of carbonyl amidation and O-methylation during biosynthesis of the pharmacophore pyridyl of antitumor piericidins

Synthetic and Systems Biotechnology, 2022
Piericidins are a large family of bacterial α-pyridone antibiotics with antitumor activities such as their anti-renal carcinoma activity exhibited recently in nude mice.
Wanlu Li, Wenyu Zhang, Yijia Cheng, Yaoyao Shen, Jianzhao Qi, Hou-Wen Lin, Yongjun Zhou   +6 more
doaj   +1 more source

A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062

Molecules, 2017
A new N-methoxypyridone analog (1), together with four known compounds, was isolated from the co-culture of Hawaiian endophytic fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062.
Chunshun Li, Ariel M. Sarotti, Baojun Yang, James Turkson, Shugeng Cao   +4 more
doaj   +1 more source

Recent Progress in Nitro-Promoted Direct Functionalization of Pyridones and Quinolones

Molecules, 2020
Nitro group is one of the most important functional groups in organic syntheses because its strongly electron-withdrawing ability activates the scaffold, facilitating the reaction with nucleophilic reagents or the Diels−Alder reaction.
Feiyue Hao, Nagatoshi Nishiwaki
doaj   +1 more source

X-RAY PHOTOELECTRON SPECTROSCOPY INVESTIGATION OF NITROGEN TRANSFORMATION IN CHINESE OIL SHALES DURING PYROLYSIS; pp. 129–145 [PDF]

Oil Shale, 2017
X-ray photoelectron spectroscopy (XPS) was used to investigate changes in nitrogen functionalities present in Chinese Huadian (HD), Maoming (MM) and Yaojie (YJ) oil shales during pyrolysis.
QI LIU, QING WANG, ZHICHAO WANG, Hongpeng Liu, JINGRU BAI   +4 more
doaj   +1 more source

4-Pyridone-3-carboxamide-1-β-d-ribonucleoside Triphosphate (4PyTP), a Novel NAD+ Metabolite Accumulating in Erythrocytes of Uremic Children: A Biomarker for a Toxic NAD+ Analogue in Other Tissues?

Toxins, 2011
We have identified a novel nucleotide, 4-pyridone 3/5-carboxamide ribonucleoside triphosphate (4PyTP), which accumulates in human erythrocytes during renal failure.
Elizabeth A. Carrey, Ryszard T. Smolenski, H. Anne Simmonds, Ewa M. Slominska, Lynnette D. Fairbanks, Elena Synesiou   +5 more
doaj   +1 more source