Synthesis and Evaluation of Antitumor and Anti-Angiogenesis Activity of Pyrone- or Pyridone-Embedded Analogs of Cortistatin A [PDF]
Marine DrugsSimplified analogs of cortistatin A were synthesized and biologically evaluated to develop novel antitumor substances that target angiogenesis. To analyze the effect of substituents at positions corresponding to C-2 and/or C-4 of the A-ring, various ...
Yuri Fujimoto +4 more
doaj +2 more sources
Synthesis and characterization of Cu and Fe (1:2) metal complexes based on their substituted pyridones acid dyes and their application on wool fabrics [PDF]
Journal of Chemistry Letters, 2022 In this study, the investigation deals with synthesis of acid dyes from 4-amino-1-(4-sulfophenyl)- 3-methyl-5-pyrazolone and their pyridone derivatives and their metal complexes (Cu (II)and Fe (II)).
Olamide Ajani +2 more
doaj +1 more source
Photoionization of 2-pyridone and 2-hydroxypyridine
Physical Chemistry Chemical Physics, 2010 We studied the photoionization of 2-pyridone and its tautomer, 2-hydroxypyridine by means of VUV synchrotron radiation coupled to a velocity map imaging electron/ion coincidence spectrometer. The photoionization efficiency (PIE) spectrum is composed of steps.
C. Poully, J. +10 more
openaire +5 more sources
Crystal structure of 4-(naphthalen-2-yl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile
Acta Crystallographica Section E: Crystallographic Communications, 2023 The synthesis and crystal structure of the title compound, C22H14N2O, are described. The title compound was synthesized by a three-component one-pot reaction in DMSO involving chalcone, cyanoacetamide and elemental sulfur as catalyst.
Thai Thanh Thu Bui +3 more
doaj +1 more source
Optimization of electrochemical decolorization of certain arylazo pyridone dyes [PDF]
Journal of the Serbian Chemical Society, 2014 Electrocatalytic decolorization of the arylazo pyridone dyes has been investigated in the presence of sodium chloride using DSA Ti/PtOx electrode in the diluted sodium hydroxide.
Mirković Jelena M. +4 more
doaj +1 more source
A microwave approach to the synthesis of certain 4-substituted phenyl-6-phenyl-3-cyano-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2014 A study of the synthesis of 4-substituted phenyl-6-phenyl-3-cyano-2-pyridones from 2-cyano-3-phenylsubstituted acrylates and acetophenone is presented. 2-Pyridones were obtained using conventional as well as microwave synthesis using solvent and
Marinković Aleksandar +4 more
doaj +1 more source
Excitation Energy-Dependent Decay Dynamics of the S1 State of N‑Methyl-2-pyridone
, 2023 The UV-induced decay dynamics of N-methyl-2-pyridone is investigated using a femtosecond time-resolved photoelectron spectroscopy method. Irradiation in the wavelength range of 339.3–258.9 nm prepares N-methyl-2-pyridone molecules with very different ...
Dongyuan Yang (8968340) +5 more
core +1 more source
, 2022 A family of anionic, formally nickel(0) complexes supported by bidentate NHC–pyridone ligands is described. The unsymmetric chelating environment and capping [K(18-crown-6)]+ countercation allow isolation of single-component, monometallic complexes in ...
C. Rose, Kennedy +4 more
core +1 more source
Enzymatic synthesis of vitamin B6 precursor [PDF]
Journal of the Serbian Chemical Society, 2013 3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Prlainović Nevena Ž. +4 more
doaj +1 more source
Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds
Journal of Saudi Chemical Society, 2021 Background: The chemistry and applications of 2-pyridone structures have recently attracted a lot of attention due to their uses as synthetic intermediates and their biological importance.
Mostafa M.K. Amer +4 more
doaj +1 more source