Results 81 to 90 of about 7,590 (215)
Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.An “on‐water” scalable Pd‐catalyzed heteroannulation delivers benzofurans and furopyridines at ultralow catalyst loadings (down to 0.005 mol%), providing products essentially free of palladium residues. In addition to a broad substrate scope (aryl, alkenyl, and alkyl alkynes with o‐iodophenols or 2‐iodo‐3‐hydroxypyridines), this protocol enables a new ...
Iratxe Astarloa +3 more
wiley +1 more source
Solid-State Supramolecular Assembly of Salicylic Acid and 2-Pyridone, 3-Hydroxypyridine or 4-Pyridone [PDF]
, 2017 Mechanochemical milling of equimolar mixtures of salicylic acid with three hydroxy derivatives of pyridine provided three new phases. With 2-hydroxypyridine, which is in fact present as 2-pyridone, a discrete cocrystal supramolecular assembly is formed ...
Halasz, Ivan +13 more
core +2 more sources
Pellagra in Contemporary Clinical Practice (2000–2023): A Systematic Review
International Journal of Dermatology, Volume 65, Issue 8, Page 1590-1599, August 2026.This systematic review (2000–2023) of 1212 cases highlights pellagra's evolving etiology. While primary dietary deficiency (85%) persists in humanitarian crises, secondary forms from alcohol misuse (9.6%), isoniazid (14.3% of drug‐related cases), and malabsorption are rising.
Noureddine Litaiem +2 more
wiley +1 more source
1-[(2-Chloro-7,8-dimethylquinolin-3-yl)methyl]pyridin-2(1H)-one
Acta Crystallographica Section E, 2010 In the title compound, C17H15ClN2O, the quinoline ring system is nearly planar, with a maximum deviation from the mean plane of 0.074 (2) Å, and makes a dihedral angle of 81.03 (7)° with the pyridone ring ...
F. Nawaz Khan +3 more
doaj +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
SYNTHETIC ROUTES AND NATURAL SOURCES OF 2-PYRIDONE DERIVATIVES AND THEIR PHARMACOLOGICAL ACTIVITY [PDF]
, 2017 Objective: 2-pyridone is a well-known heterocyclic ring having significant biological and medical application. The molecular structures and various activities of 2-pyridone derivatives as well as their syntheses and natural occurrence are analyzed and ...
MISHRA, PREM SHANKAR +2 more
core +4 more sources
Diversity-oriented functionalization of 2-pyridones and uracils
Nature Communications, 2021 Diversity-oriented synthesis of 2-pyridone and uracil derivatives is in urgent need in medicinal chemistry as they are useful pharmacophores. Here the authors show that palladium/norbornene cooperative catalysis enabled dual-functionalization of ...
Yong Shang +8 more
doaj +1 more source
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 27, 17 July 2026.Total syntheses of agelamadin F and (±)‐tauroacidin A were achieved by sodium chlorite (NaClO2)‐mediated oxidative C─N coupling. Nine C15–N–amino acid‐substituted oroidin derivatives were successfully prepared to demonstrate the applicability and versatility of this oxidative coupling reaction.
Ryosuke Hirozumi +3 more
wiley +1 more source
Synthesis, structure and solvatochromic properties of 3-cyano-4,6-diphenyl-5-(3- and 4-substituted phenylazo)-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2010 A series of some new pyridone arylazo dyes was synthesized from the corresponding diazonium salts and 3-cyano-4,6-diphenyl-2-pyridone using the classical reaction for the synthesis of the azo compounds.
NINA TODOROVIĆ +5 more
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