Results 81 to 90 of about 8,502 (208)

2-Bromopyridines as Versatile Synthons for Heteroarylated 2-Pyridones via Ru(II)-Mediated Domino C–O/C–N/C–C Bond Formation Reactions

open access: yesMolecules
A novel methodology for the synthesis of 2-pyridones bearing a 2-pyridyl group on nitrogen and carbon atoms, starting from 2-bromopyridines, was developed employing a simple Ru(II)–KOPiv–Na2CO3 catalytic system.
Miha Drev   +6 more
doaj   +1 more source

Crystal Chemistry of Zinc Quinaldinate Complexes with Pyridine-Based Ligands

open access: yesCrystals, 2018
Substitution of methanol in [Zn(quin)2(CH3OH)2] (quin− denotes an anionic form of quinoline-2-carboxylic acid, also known as quinaldinic acid) with pyridine (Py) or its substituted derivatives, 3,5-lutidine (3,5-Lut), nicotinamide (Nia), 3 ...
Barbara Modec
doaj   +1 more source

An overview of synthesis and biological activities of 2-pyridone derivatives over the last decade

open access: yesDiscover Applied Sciences
2-Pyridone frameworks are a pervasive member of the N-heterocyclic family of both chemical and therapeutic interest. 2-Pyridones and their bridged analogues have wide occurrences in nature and the presence of both aromatic and amide groups in the ...
Lopamudra Das, Tista Sengupta
doaj   +1 more source

2-Pyridone: monoclinic polymorph

open access: yesActa Crystallographica Section E, 2009
The asymmetric unit in the title compound, C5H5NO, comprises two independent but virtually identical molecules of 2-pyridone, and represents a monoclinic polymorph of the previously reported orthorhombic (P212121) form [Penfold (1953). Acta Cryst. 6, 591&
Edward R. T. Tiekink   +2 more
doaj   +1 more source

Pyridone-based nucleotide analogues accepted for DNA biosynthesis

open access: yes, 2017
Novel pyridone-based nucleotides were investigated for maintenance of DNA synthesis, carried on by representatives of different classes of polymerases. Five different nucleoside triphosphates of similar structure were addressed, demonstrating involvement
Bazilė Ravoitytė   +3 more
core   +1 more source

Total synthesis of (−)-epimyrtine by a gold-catalyzed hydroamination approach

open access: yesBeilstein Journal of Organic Chemistry, 2013
A new approach to the total synthesis of (−)-epimyrtine has been developed from D-alanine. The key step to access the enantiopure pyridone intermediate was achieved by a gold-mediated cyclization.
Thi Thanh Huyen Trinh   +3 more
doaj   +1 more source

Correction to 2‑Pyridone Synthesis Using 2‑(Phenylsulfinyl)acetamide

open access: yes, 2016
Correction to 2‑Pyridone Synthesis Using 2‑(Phenylsulfinyl ...
Takahiro Koshiba (1843504)   +4 more
core   +1 more source

A Diels-alder Route To Pyridone and Piperidone Derivatives

open access: yes, 1982
A Diels-alder Route To Pyridone and Piperidone ...
Ghosez, Léon   +3 more
core   +1 more source

Synthesis and Evaluation of Antitumor and Anti-Angiogenesis Activity of Pyrone- or Pyridone-Embedded Analogs of Cortistatin A

open access: yesMarine Drugs
Simplified analogs of cortistatin A were synthesized and biologically evaluated to develop novel antitumor substances that target angiogenesis. To analyze the effect of substituents at positions corresponding to C-2 and/or C-4 of the A-ring, various ...
Yuri Fujimoto   +4 more
doaj   +1 more source

Examining the safety of nicotinamide for skin cancer prevention: Review of adverse events, metabolism, and toxic dosages

open access: yesJAAD Reviews
Nicotinamide (niacinamide) supplementation for non-melanoma skin cancer prevention has sparked controversy over the past decade due to its inconsistent evidence of chemoprevention and its recently challenged safety profile.
Katie R. Xu, BA   +2 more
doaj   +1 more source

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