Results 71 to 80 of about 7,582 (216)

Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products

Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman, Mathieu Frenette, Sylvain Canesi   +2 more
wiley   +1 more source

Surface‐Bound Superoxide Radical‐Mediated Photo‐Fenton Mineralization of Ciprofloxacin on Fe‐Sillenite Nanosheets

Advanced Science, Volume 13, Issue 29, 22 May 2026.
This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu, Ji Liu, Hengjun Shang, Yaning Zhang, Shuai Dou, Jing Xu, Ying Zhang, Yang Lou, Yongfa Zhu, Chengsi Pan   +9 more
wiley   +1 more source

Dipole moment studies of some derivatives of 4-pyridone

, 1972
The dipole moments of 13 derivatives of 4-pyridone were measured. Attempts to obtain a value for 4-pyridone were unsuccessful but a value of 6.O D is compatible with other evidence. Dipole moment and n.m.r, evidence indicated that for N-phenyl-4-pyridone
BD Batts, AJ Madeley
core   +1 more source

Defect‐Regulated Electronic and Lattice Evolution in Na4VMn(PO4)3 Toward High‐Performance Sodium Storage

Rare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT NASICON‐type Na4VMn(PO4)3 (NVMP) is a promising high‐capacity cathode for sodium‐ion batteries, yet its practical deployment is hindered by Mn3+‐driven lattice distortion, persistent oxygen vacancy defects, and sluggish Na+ transport, collectively resulting in accelerated performance degradation.
Deyi Zhang, Fan Li, Lin Zhou, Weiliang Xu, Shuoshuo Cheng, Xiaohui Rong, Weihe Kong, Shiyu Li, Quan Zhou, Junmei Zhao, Ying Bai   +10 more
wiley   +1 more source

Pyridone-substituted Pyridyl imines as Functionalised ligands in Coordination Chemistry and Catalysis

, 2018
In this thesis, the synthesis and coordination chemistry of a series of novel NNN and NN proton responsive ligands are described. All the ligands and complexes have been characterized by a combination of multinuclear NMR spectroscopic techniques, mass ...
Mona Hanash A. Alhalafi (7716149)
core   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

British Journal of Pharmacology, Volume 183, Issue 10, Page 2219-2235, May 2026.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind, Shane C. Wright, Emilia Gvozdenovic, Kristina Nilsson, Kenneth L. Granberg, Michel Bouvier, Linda C. Johansson   +6 more
wiley   +1 more source

Ester-Amide Exchange Reactions Using 2-Pyridone derivatives as Tautomeric Catalysts

The application of 2-pyridone as a tautomeric catalyst for ester-amide exchange reactions was investigated. This compound was found to be most effective at accelerating these reactions when 4-nitrophenyl acetate was used as an acylating agent in toluene.
Misao, Yotsuji, Ayumi, Imayoshi, Kanako, Mihara, Kazunori, Tsubaki   +3 more
core   +1 more source

Safety of beta‐nicotinamide mononucleotide (β‐NMN) pursuant the regulation (EU) 2015/2283 and the bioavailability of nicotinamide from this source in the context of Directive 2002/46/EC

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on beta‐nicotinamide mononucleotide (β‐NMN) as a novel food (NF) pursuant to Regulation (EU) 2015/2283, including an evaluation of the safety of its use in food supplements as a source of niacin ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Ursula Gundert‐Remy, Francesca Marcon, Harry J. McArdle, Monika Neuhäuser‐Berthold, Miguel Prieto Maradona, Alexandros Siskos, Matthew Wright, Elisa Beneventi, Annamaria Rossi, Maura Magani, Karen Ildico Hirsch‐Ernst   +28 more
wiley   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Facile synthesis and cytotoxicity of substituted uracil-1'(N)-acetic acid and 4-pyridone-1'(N)-acetic acid esters of 20(S)-camptothecins

A series of novel substituted uracil-1'(N)-acetic acid esters (5–9) and 4-pyridone-1'(N)-acetic acid esters (10–11) of 20(S)-camptothecins (CPTs) have been synthesized by the acylation method.
Di-Zao Li (17955359), Zhao-Di Fu (17955362), Hong-Yan Liu (6290597), Xian-Dao Pan (17955365)   +3 more
core   +1 more source