Results 61 to 70 of about 7,590 (215)
Beilstein Journal of Organic Chemistry, 2012 A core 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-one scaffold is elaborated at C-3(Me) by base-mediated aldol condensation to give new 3-alkenyl-4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-ones, which are masked forms related to the acylpyridone ...
Raymond C. F. Jones +5 more
doaj +1 more source
Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2019 In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana +3 more
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Biosynthesis of (–)-Sambutoxin, a Fusarium 2-Pyridone Alkaloid Mycotoxin [PDF]
, 2021 This dissertation describes the discovery by genome mining and the characterization of thebiosynthetic pathway for sambutoxin, a 4-hydroxy-2-pyridone alkaloid Fusarium mycotoxin.
Go, Louise
core
Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles
Angewandte Chemie International Edition, EarlyView.Saturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Arthur Despois, Nicolai Cramer
wiley +1 more source
Facile synthesis and cytotoxicity of substituted uracil-1'(N)-acetic acid and 4-pyridone-1'(N)-acetic acid esters of 20(S)-camptothecins [PDF]
A series of novel substituted uracil-1'(N)-acetic acid esters (5–9) and 4-pyridone-1'(N)-acetic acid esters (10–11) of 20(S)-camptothecins (CPTs) have been synthesized by the acylation method.
Di-Zao Li (17955359) +3 more
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SYNTHESIS AND ANTIHYPERLIPIDEMIC ACTIVITY OF CERTAIN NICOTINIC ACID DERIVATIVES [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2005 3-Ethoxycarbonyl-4,6-dimethyl-2(1H)-pyridone I was prepared and converted to the corresponding sodium salt II. The latter reacted with certain chloroacetanilides to afford the corresponding ethers III.
Mohamed Abdel-Wahab +1 more
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Synthesis of 2-Pyridone Derivatives Bearing an Electron-withdrawing Group on Nitrogen [PDF]
, 2007 1-Protected 2(1H)-pyridones are highly useful dienophiles because Diels-Alder reaction of 1-sulfonyl-2(1H)-pyridones gave the synthetic intermediate such as quinoline and isoquinoline derivatives.
渡邉, 一弘 +8 more
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Solid-Phase Synthesis of Diverse Macrocycles By Regiospecific 2-Pyridone Formation: Scope and Applications [PDF]
This study introduces a novel solid-phase macrocyclization method generating 2-pyridone rings. This method relies on the intramolecular condensation between secondary and tertiary dimethoxy-propionic amide (DMPA) units.
Thomas, Kodadek, Skander, Abboud
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Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.Leigh's metal‐free active template‐based SNAr of an amine on halogenopyridiniums, in the presence of a crown ether, successfully afforded 4‐aminopyridinium‐containing rotaxanes. Further molecular machinery was carried out by deprotonation‐then‐carbamoylation of the conjugated amino moiety.
Ivaylo Stoyanov +2 more
wiley +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2017 In the title compound, C21H17N5O3S3·C3H7NO, the toluenesulfonamide ring and the combined ring system involving the pyridone and benzothiazole rings subtend an interplanar angle of 39.86 (4)°.
Rasha A. Azzam +3 more
doaj +1 more source