3-Cyano-4,6-dimethyl-2-pyridone (Guareschi pyridone)
Acta Crystallographica Section E Structure Reports Online, 2004 In the crystal structure of the title compound, C8H8N2O, the molecules form centrosymmetric dimers via N—H⋯O hydrogen bonds.
Victor B. Rybakov +3 more
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Dipole moment studies of some derivatives of 4-pyridone [PDF]
, 1972 The dipole moments of 13 derivatives of 4-pyridone were measured. Attempts to obtain a value for 4-pyridone were unsuccessful but a value of 6.O D is compatible with other evidence. Dipole moment and n.m.r, evidence indicated that for N-phenyl-4-pyridone
BD Batts, AJ Madeley
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Synthesis of 5-(substituted phenylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones from ethyl 3-oxo-2-(substituted phenylazo)butanoates, Short communication [PDF]
Journal of the Serbian Chemical Society, 2011 A new procedure for the synthesis of known azo pyridone dyes is presented. A series of 5-(substituted arylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones were prepared from ethyl 3-oxo-2-(substituted phenylazo)butanoates and cyanoacetamide in acetone using ...
GORDANA UŠĆUMLIĆ +3 more
doaj
Heterocyclic Communications, 2022 2-Pyridone is considered as one of the most famous efficient pharmaceutical compounds. Many approaches were discovered to synthesize 2-pyridone. In this present research, chloroacetylation of benzylamine at simple conditions, EtONa/EtCOONa produced N ...
Hamed Eman O. +4 more
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Pyridone-substituted Pyridyl imines as Functionalised ligands in Coordination Chemistry and Catalysis [PDF]
, 2018 In this thesis, the synthesis and coordination chemistry of a series of novel NNN and NN proton responsive ligands are described. All the ligands and complexes have been characterized by a combination of multinuclear NMR spectroscopic techniques, mass ...
Mona Hanash A. Alhalafi (7716149)
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5,5’-Selenobis(1-benzyl-2-oxo-1,2-dihydropyridine-4-carbaldehyde)
MolbankSelenium compounds have garnered significant attention in the field of medicinal chemistry due to their unique biochemical properties and potential therapeutic applications for different pathologies.
Emeline Grosjean +5 more
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Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection
Journal of Genetic Engineering and Biotechnology, 2023 Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate,
Magda M. F. Ismail +8 more
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Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium
Angewandte Chemie, EarlyView.Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner +2 more
wiley +1 more source
Ester-Amide Exchange Reactions Using 2-Pyridone derivatives as Tautomeric Catalysts [PDF]
The application of 2-pyridone as a tautomeric catalyst for ester-amide exchange reactions was investigated. This compound was found to be most effective at accelerating these reactions when 4-nitrophenyl acetate was used as an acylating agent in toluene.
Misao, Yotsuji +3 more
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New Pyridone-Based Derivatives as Cannabinoid Receptor Type 2 Agonists [PDF]
, 2021 The activation of the human cannabinoid receptor type II (CB2R) is known to mediate analgesic and anti-inflammatory processes without the central adverse effects related to cannabinoid receptor type I (CB1R).
Faundez Parraguez, Manuel +16 more
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