Results 1 to 10 of about 9,290 (210)

Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds [PDF]

open access: yesHemijska Industrija, 2014
2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications.
Mijin Dušan Ž.   +3 more
doaj   +4 more sources

2-Bromopyridines as Versatile Synthons for Heteroarylated 2-Pyridones via Ru(II)-Mediated Domino C–O/C–N/C–C Bond Formation Reactions [PDF]

open access: yesMolecules
A novel methodology for the synthesis of 2-pyridones bearing a 2-pyridyl group on nitrogen and carbon atoms, starting from 2-bromopyridines, was developed employing a simple Ru(II)–KOPiv–Na2CO3 catalytic system.
Miha Drev   +6 more
doaj   +2 more sources

Metal-Free Cascade Formation of C–C and C–N Bond for the Construction of 3-Cyano-2-Pyridones with Insecticidal Properties [PDF]

open access: yesMolecules
A straightforward and efficient methodology has been developed for the synthesis of 3-cyano-2-pyridones via the C–C and C–N bond formation processes. A total of 51 diverse 3-cyano-2-pyridone derivatives were obtained in moderate to excellent yields. This
Yao Tang   +5 more
doaj   +2 more sources

A microwave approach to the synthesis of certain 4-substituted phenyl-6-phenyl-3-cyano-2-pyridones [PDF]

open access: yesJournal of the Serbian Chemical Society, 2014
A study of the synthesis of 4-substituted phenyl-6-phenyl-3-cyano-2-pyridones from 2-cyano-3-phenylsubstituted acrylates and acetophenone is presented. 2-Pyridones were obtained using conventional as well as microwave synthesis using solvent and
Marinković Aleksandar   +4 more
doaj   +1 more source

Recent Progresses in the Catalytic Stereoselective Dearomatization of Pyridines

open access: yesMolecules, 2023
1,2- and 1,4-dihydropyridines and N-substituted 2-pyridones are very important structural motifs due to their synthetic versatility and vast presence in a variety of alkaloids and bioactive molecules.
Lucrezia Margherita Comparini   +1 more
doaj   +1 more source

Computational studies by molecular docking of some antiviral drugs with COVID-19 receptors are an approach to medication for COVID-19

open access: yesOpen Chemistry, 2021
The COVID-19 outbreak is a matter of concern worldwide due to unavailability of promising treatment comprising medication or vaccination till date. The discovery of antiviral drug is of immense importance in the existing spread of novel coronavirus.
Abdellatiif Magda H.   +3 more
doaj   +1 more source

Synthesis and Characterization of New 3-Cyano-2-Pyridone Derivatives as Fluorescent Scaffolds

open access: yesChemistry Proceedings, 2023
2-pyridones are among the most widely used nitrogen-containing heterocyclic derivatives in various fields due to their structural properties and biological and therapeutic activities.
Asmaa Kebaili   +5 more
doaj   +1 more source

Manganese(II) β-Diketonate Complexes with Pyridin-4-one, 3-Hydroxypyridin-2-one and 1-Fluoropyridine Ligands: Molecular Structures and Hydrogen-bonded Networks

open access: yesActa Chimica Slovenica, 2021
Manganese(II) bis(4,4,4-trifluoro-1-phenylbutane-1,3-dionate) complexes with pyridin-4-one (pyon), 3-hydroxypyridin-2-one (hpyon), 1-fluoropyridine (pyF) and methanol were prepared and the solid-state structures were determined by single-crystal X-ray ...
Anže Čavić, Franc Perdih
doaj   +1 more source

Divergent rhodium-catalyzed electrochemical vinylic C–H annulation of acrylamides with alkynes

open access: yesNature Communications, 2021
α-Pyridones and α-pyrones are ubiquitous structural motifs found in natural products and components of biologically active small molecules. Here, the authors report an oxidant-free Rh-catalyzed electrochemical divergent vinylic C–H annulation of ...
Yi-Kang Xing   +6 more
doaj   +1 more source

A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes

open access: yesmBio, 2023
Listeria monocytogenes is a facultative Gram-positive bacterium that causes listeriosis, a severe foodborne disease. We previously discovered that ring-fused 2-pyridone compounds can decrease virulence factor expression in Listeria by binding and ...
Hasan Tükenmez   +10 more
doaj   +1 more source

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