Results 231 to 240 of about 20,092 (323)

Multifocal Renal Infarction and Diabetic Ketoacidosis: Diagnostic Challenges and Anticoagulation Management in a Complex Case. [PDF]

Am J Case Rep
Miles L, Shin B, Ji H, Ghaffari-Rafi S, Chitsazan M, Kim DI.   +5 more
europepmc   +1 more source

Comparison between low molecular weight heparin and apixaban (direct oral anticoagulant) in the prophylaxis against venous thromboembolism after laparoscopic sleeve gastrectomy. [PDF]

Obes Surg
Abdelsalam A, Fikry M, Fahmy A, Hegazy T, Hamdy A, Refaat A, Elansary A.   +6 more
europepmc   +1 more source

Metallaelectro-catalyzed alkyne annulations via C-H activations for sustainable heterocycle syntheses.

Chem Commun (Camb)
Kushwaha P, Saxena A, von Münchow T, Dana S, Saha B, Ackermann L.   +5 more
europepmc   +1 more source

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Cobalt(III)-Catalyzed Regioselective C6 Olefination of 2-Pyridones Using Alkynes: Olefination/Directing Group Migration and Olefination

Organic Letters, 2021
Co(III)-catalyzed highly regio- and stereoselective direct C6 olefination of 2-pyridones with alkynes has been developed with the assistance of chelation.
Haoqiang Zhao, Lijin Xu, Ming Lei
exaly   +2 more sources

Bioevaluation of synthetic pyridones as dual inhibitors of α‐amylase and α‐glucosidase enzymes and potential antioxidants

Archiv der Pharmazie, 2022
Herein, a library of novel pyridone derivatives 1–34 was designed, synthesized, and evaluated for α‐amylase and α‐glucosidase inhibitory as well as antioxidant activities.
F. Saleem, K. Khan, N. Ullah, M. Özil, N. Baltaş, S. Hameed, U. Salar, A. Wadood, A. Rehman, Mukesh Kumar, M. Taha, S. M. Haider   +11 more
semanticscholar   +1 more source

Ruthenium-Catalyzed Chemoselective N-H Bond Insertion Reactions of 2-Pyridones/7-Azaindoles with Sulfoxonium Ylides.

Organic Letters, 2021
A ruthenium-catalyzed highly chemoselective N-alkylation of 2-pyridones has been developed, affording N-alkylated 2-pyridone derivatives in good yields and excellent N-selectivity.
Xiaofeng Liu, Y. Shao, Jiangtao Sun
semanticscholar   +1 more source

Alkynyl Triazenes as Fluoroalkyne Surrogates: Regioselective Access to 4-Fluoro-2-pyridones by a Rh(III)-Catalyzed C–H Activation–Lossen Rearrangement–Wallach Reaction

ACS Catalysis, 2020
Fluorinated pyridones are an important scaffold displaying relevant biological activities. Efficient assembly strategies of pyridones are transition metal-catalyzed C–H annulations with alkynes.
Jin-fay Tan, Kay Severin, Nicolai Cramer
exaly   +2 more sources

Chemo- and Enantioselective Insertion of Furyl Carbene into the N-H Bond of 2-Pyridones.

Angewandte Chemie, 2021
Asymmetric carbene insertion reactions represent one of the most important protocols to construct carbon-heteroatom bonds. The use of donor-acceptor diazo compounds bearing an ester group is however a prerequisite for achieving high enantioselectivity ...
Kai Wang, Zi‐Ye Liu, Guangyang Xu, Y. Shao, S. Tang, Ping-Fan Chen, Xinhao Zhang, Jiangtao Sun   +7 more
semanticscholar   +1 more source

Chemoselective N- and O-Difluoromethylation of 2-Pyridones, Isoquinolinones, and Quinolinones with TMSCF2Br.

Organic Letters, 2021
An operationally simple protocol for direct N- and O-difluoromethylation of 2-pyridones, quinolinones, and isoquinolinones using commercially available TMSCF2Br is disclosed. The chemoselectivity is modulated by simple variations in temperature, solvent,
Ziyue Zhu, V. Krishnamurti, Xanath Ispizua-Rodriguez, C. Barrett, G. Prakash   +4 more
semanticscholar   +1 more source

Copper-Catalyzed Regioselective Coupling of Tosylhydrazones and 2-Pyridones: A Strategy for the Production of N-Alkylated Compounds.

Journal of Organic Chemistry, 2021
The highly regioselective N-alkylation reaction of 2-pyridones was achieved through hydrazone chemistry, especially for substrates with bulky secondary alkyl groups.
Ye-bin Wu, Youzhi Wu, Jian Wu, Danqian Xu, Hui Jiang, Wenxu Chang, Chang-You Ma   +6 more
semanticscholar   +1 more source