Results 241 to 250 of about 20,827 (302)
Some of the next articles are maybe not open access.
, 2020
Fluorinated pyridones are an important scaffold displaying relevant biological activities. Efficient assembly strategies of pyridones are transition metal-catalyzed C–H annulations with alkynes.
Jin-Fay Tan +3 more
semanticscholar +1 more source
Fluorinated pyridones are an important scaffold displaying relevant biological activities. Efficient assembly strategies of pyridones are transition metal-catalyzed C–H annulations with alkynes.
Jin-Fay Tan +3 more
semanticscholar +1 more source
ChemInform Abstract: PHOTOISOMERIZATION OF 4‐PYRIDONES TO 2‐PYRIDONES
Chemischer Informationsdienst, 1974AbstractBestrahlung (Hg‐Mitteldrucklampe) der 4‐Pyridone (I) liefert die isomeren 2‐Pyridone (II) als Hauptprodukte, während die 4‐Pyridone (III) unter gleichen Bedingungen unverändert bleiben.
NOBUYUKI ISHIBE, JUN MASUI
openaire +1 more source
Journal of Organic Chemistry, 2020
A mild, catalyst- and metal-free photochemical protocol for the oxygenation of 3-cyano-1,4-dihydropyridines to 5-cyano-2-pyridones was developed. Utilizing molecular oxygen from air as the oxidant and a cheap blue LED lamp as the light source, a variety ...
Mengmeng Zhang +6 more
semanticscholar +1 more source
A mild, catalyst- and metal-free photochemical protocol for the oxygenation of 3-cyano-1,4-dihydropyridines to 5-cyano-2-pyridones was developed. Utilizing molecular oxygen from air as the oxidant and a cheap blue LED lamp as the light source, a variety ...
Mengmeng Zhang +6 more
semanticscholar +1 more source
Journal of Organic Chemistry, 2020
We have identified different N-substituted 2-pyridones as inbuilt directing groups for selective C-H-activated functionalization instead of deprotecting and/or throwing away the directing groups.
Tanmay K. Pati +5 more
semanticscholar +1 more source
We have identified different N-substituted 2-pyridones as inbuilt directing groups for selective C-H-activated functionalization instead of deprotecting and/or throwing away the directing groups.
Tanmay K. Pati +5 more
semanticscholar +1 more source
Journal of the Chemical Society, Chemical Communications, 1985
Lithiation of 1-methyl-4-pyridone with n-butyl-lithium at -78 °C proceeds smoothly at the C-2 position and 2-substituted-4-pyridones (1c–j) are obtained by subsequent reaction with electorphiles; lithiation of 1-methyl-2-pyridone takes place predominantly at the N-methyl, the lithio-derivative reacting rapidly, even at -78 °C with starting pyridone to ...
Premji Patel, John A. Joule
openaire +1 more source
Lithiation of 1-methyl-4-pyridone with n-butyl-lithium at -78 °C proceeds smoothly at the C-2 position and 2-substituted-4-pyridones (1c–j) are obtained by subsequent reaction with electorphiles; lithiation of 1-methyl-2-pyridone takes place predominantly at the N-methyl, the lithio-derivative reacting rapidly, even at -78 °C with starting pyridone to ...
Premji Patel, John A. Joule
openaire +1 more source
Angewandte Chemie, 2018
Cu-catalyzed redox-divergent [3+3] coupling of oxime esters with β-CF3 enones and acrylates is described. This redox-neutral coupling with enones and acrylates affords trifluoromethylated pyridines and pyridones, respectively. Under reductive conditions,
Dachang Bai +3 more
semanticscholar +1 more source
Cu-catalyzed redox-divergent [3+3] coupling of oxime esters with β-CF3 enones and acrylates is described. This redox-neutral coupling with enones and acrylates affords trifluoromethylated pyridines and pyridones, respectively. Under reductive conditions,
Dachang Bai +3 more
semanticscholar +1 more source
Journal of Organic Chemistry, 2020
2,3-Dihydro-4-pyridone skeleton is an important building block in organic synthesis because it features several reaction sites with nucleophilic or electrophilic properties.
M. Stojanović +2 more
semanticscholar +1 more source
2,3-Dihydro-4-pyridone skeleton is an important building block in organic synthesis because it features several reaction sites with nucleophilic or electrophilic properties.
M. Stojanović +2 more
semanticscholar +1 more source
Journal of the Chemical Society B: Physical Organic, 1968
The reaction between N-alkyl-2-pyridones and tetracyanoethylene produces 2 : 1 salts of the pyridone with pentacyanopropene. Metathetical exchange of these salts with 4H-quinolizin-4-one leads to mono- and bis-quinolizone salts. Similar salts are formed with hydroquinone in place of pentacyanopropene.
B. S. Thyagarajan +2 more
openaire +1 more source
The reaction between N-alkyl-2-pyridones and tetracyanoethylene produces 2 : 1 salts of the pyridone with pentacyanopropene. Metathetical exchange of these salts with 4H-quinolizin-4-one leads to mono- and bis-quinolizone salts. Similar salts are formed with hydroquinone in place of pentacyanopropene.
B. S. Thyagarajan +2 more
openaire +1 more source
Pyridones as Potential Antitumor Agents
Journal of Pharmaceutical Sciences, 1979Based on the finding that 3-acetoxy-2-pyridone had reproducible activity against murine P-388 lymphocytic leukemia, derivatives in this series were synthesized and evaluated to determine structural parameters important for activity. Of the 32 compounds tested, 10 were active.
D R, Hwang, J S, Driscoll
openaire +2 more sources
Ambident Reactivities of Pyridone Anions
Journal of the American Chemical Society, 2010The kinetics of the reactions of the ambident 2- and 4-pyridone anions with benzhydrylium ions (diarylcarbenium ions) and structurally related Michael acceptors have been studied in DMSO, CH(3)CN, and water. No significant changes of the rate constants were found when the counterion was varied (Li(+), K(+), NBu(4)(+)) or the solvent was changed from ...
Martin, Breugst, Herbert, Mayr
openaire +2 more sources