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Redox‐Divergent Synthesis of Fluoroalkylated Pyridines and 2‐Pyridones through Cu‐Catalyzed N−O Cleavage of Oxime Acetates

Angewandte Chemie - International Edition, 2018
Cu-catalyzed redox-divergent [3+3] coupling of oxime esters with β-CF3 enones and acrylates is described. This redox-neutral coupling with enones and acrylates affords trifluoromethylated pyridines and pyridones, respectively. Under reductive conditions,
B Kanimozhi, Xueli Wang, Guangfan Zheng
exaly   +2 more sources

Ligand-Controlled Ni(0)–Al(III) Bimetal-Catalyzed C3–H Alkenylation of 2-Pyridones by Reversing Conventional Selectivity

, 2021
Conventional C–H alkenylation with alkynes via low-valent transition-metal catalysis occurs at the C6 or C4 position of 2-pyridone with electron-deficient C–H bonds.
Ge Yin   +6 more
semanticscholar   +1 more source

ChemInform Abstract: PHOTOISOMERIZATION OF 4‐PYRIDONES TO 2‐PYRIDONES

Chemischer Informationsdienst, 1974
AbstractBestrahlung (Hg‐Mitteldrucklampe) der 4‐Pyridone (I) liefert die isomeren 2‐Pyridone (II) als Hauptprodukte, während die 4‐Pyridone (III) unter gleichen Bedingungen unverändert bleiben.
Nobuyuki Ishibe, Jun Masui
openaire   +3 more sources

Lithiation of pyridones

Journal of the Chemical Society, Chemical Communications, 1985
AbstractDie selektive Lithiiemng des N‐Methylpyridons (I) und anschließende Umsetzung von (II) mit Elektrophilen ergibt die Z‐sulastittnierten Pyridone (III).
Premji Patel, John A. Joule
openaire   +3 more sources

Pyridones as Potential Antitumor Agents II: 4-Pyridones and Bioisosteres of 3-Acetoxy-2-pyridone

Journal of Pharmaceutical Sciences, 1980
Pyridone structural requirements for activity against murine P-388 leukemia have been extended to isosteric analogs of 3-hydroxy-4-pyridone, a compound previously found to have activity. An amino group can be substituted for the 3-hydroxyl function with retention of activity.
John S. Driscoll   +3 more
openaire   +3 more sources

4-Hydroxy Pyridones from Heterologous Expression and Cultivation of the Native Host.

Journal of Natural Products, 2020
4-Hydroxy pyridones are a class of fungi-derived polyketide-nonribosomal peptide products featuring a core of 4-hydroxy-2-pyridone which have a wide range of biological activities.
Wei-Yang Zhang   +12 more
semanticscholar   +1 more source

Tetrachlorobis(2-pyridone)-bis(μ2-2-pyridone)-dicopper

Acta Crystallographica Section C Crystal Structure Communications, 1993
In this structure two Cu II centres 3.4448 (11) A apart are bridged asymmetrically by two 2-pyridone ligands and each is further coordinated by three terminal ligands (two chlorides and one 2-pyridone). Each molecule has an approximate, non-crystallographic centre of symmetry.
R. E. P. Winpenny, A. J. Blake
openaire   +2 more sources

Rh(I)-Catalyzed C6-Selective Decarbonylative Alkylation of 2-Pyridones with Alkyl Carboxylic Acids and Anhydrides.

Organic Letters, 2020
A Rh-catalyzed chelation-assisted C6-selective C-H activation/alkylation of 2-pyridones with readily available alkyl carboxylic acids or anhydrides is introduced. The reaction proceeds via substrate decarbonylation.
Haoqiang Zhao   +8 more
semanticscholar   +1 more source

ChemInform Abstract: Synthesis of Pyridines and Pyridones.

Chemischer Informationsdienst, 1984
AbstractDie Synthese einiger Furobenzopyranone, Pyridine und Pyridone auf Basis der Naturstoffe Visnagin und Khellin wird beschrieben.
Madiha M. Y. Zohair   +2 more
openaire   +2 more sources

Photocatalyst-Free Singlet Oxygen-Induced Oxygenation: A Strategy for the Preparation of 5-Cyano-2-Pyridones Driven by Blue-Light Irradiation.

Journal of Organic Chemistry, 2020
A mild, catalyst- and metal-free photochemical protocol for the oxygenation of 3-cyano-1,4-dihydropyridines to 5-cyano-2-pyridones was developed. Utilizing molecular oxygen from air as the oxidant and a cheap blue LED lamp as the light source, a variety ...
Mengmeng Zhang   +6 more
semanticscholar   +1 more source

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