Results 91 to 100 of about 60,073 (254)

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

Epilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri, Oluyomi Adesoji, Roland Krause, Patrick May, Holger Lerche, Albert Becker, Daniela Grimm, International League Against Epilepsy Consortium on Complex Epilepsies, Michael Nothnagel, Herbert Schulz   +9 more
wiley   +1 more source

Vitamin B6 metabolites in idiopathic calcium stone formers: no evidence for a link to hyperoxaluria [PDF]

, 2018
Vitamin B6 metabolites and their potential correlates to urinary oxalate excretion in idiopathic calcium stone formers (ICSF) compared with healthy subjects were investigated.
Casez, Jean-Paul, Jaeger, Philippe, Kaelin, Agnes   +2 more
core  

Selection for Postponed Senescence in Drosophila melanogaster Reveals Distinct Metabolic Aging Trajectories Modifiable by the Angiotensin-Converting Enzyme Inhibitor Lisinopril. [PDF]

Aging Cell
Assessment of oxygen consumption rates in young, middle‐aged, and old flies from the Drosophila B lines and long‐lived O lines revealed a significant increase in metabolic rate with aging only in B flies. Lisinopril prevented the age‐related rise in metabolic rate in B female flies.
Vecchié D, Anholt RRH, Mackay TFC, De Luca M.   +3 more
europepmc   +2 more sources

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

International Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh, Lucília da P. da Silva, Carlos A. Pinto, Rosário Martins, Alexandra P. Marques, Jorge A. Saraiva   +5 more
wiley   +1 more source

Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

Pteridines, 2002
Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography.
Rudzite Vera, Jurika Edite, Kalnins Uldis, Erglis Andrejs, Trusinskis Karlis, Jegere Sanda, Frick Barbara, Fuchs Dietmar   +7 more
doaj   +1 more source

First attempt at using a synthetic diet in short‐lived killifish, a vertebrate model of ageing

Journal of Fish Biology, EarlyView.
Abstract Diet standardization of model organisms is crucial for experimental consistency and repeatability in laboratory research, yet laboratory fish often lack species‐specific, open‐formula standardized diets. This study aims to address this gap by testing the effect of macronutrient content on the performance of Nothobranchius furzeri, an ...
Jakub Žák, Milan Vrtílek
wiley   +1 more source

Do dietary patterns in older men influence change in homocysteine through folate fortification? The Normative Aging Study [PDF]

Objective We aimed to describe the difference in B-vitamin intake and in plasma B-vitamin and homocysteine concentrations before and after folic acid fortification, in relation to dietary patterns. Design The Normative Aging Study (NAS) is a longitudinal
Groot, C.P.G.M., de, Knoops, K.T.B., Kromhout, D., Spiro, A., Staveren, W.A., van, Tucker, K.L.   +5 more
core   +2 more sources

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source

P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes [PDF]

, 2008
ATP plays an important role in signal transduction between neuronal and glial circuits and within glial networks. Here we describe currents activated by ATP in astrocytes acutely isolated from cortical brain slices by non-enzymatic mechanical ...
Kirchhoff, Frank, Lalo, Ulyana, North, R. Alan, Pankratov, Yuriy, Rossner, Moritz J., Verkhratskiĭ, A. N. (Alekseĭ Nestorovich), Wichert, Sven P.   +6 more
core   +1 more source

Synthesis, Structural Characterization, Cytotoxicity, and Antibacterial Properties of Gold(III) Complexes with Hydrazones Derived from Vitamin B₆

Inorganics
The rise in the number of cancer cases and the dissemination of strains with multiple drug resistance in the world pose a serious threat to public health care and human well-being.
Daria V. Petrova, Aleksandra K. Isagulieva, Olga N. Sineva, Vera S. Sadykova, Maksim N. Zavalishin, George A. Gamov   +5 more
doaj   +1 more source