Results 101 to 110 of about 63,427 (306)

Reaction of Furanoeremophilans with Pyridoxal

Natural Product Communications, 2008
Furanoeremophilan-10β-ol, a major component of Ligularia cymbulifera growing in northwestern Yunnan Province of China, reacted with pyridoxal or its 5′-phosphate at room temperature in aqueous solution to afford condensation products.
Atsushi Torihata, Chiaki Kuroda
doaj   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

Pteridines, 2002
Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography.
Rudzite Vera, Jurika Edite, Kalnins Uldis, Erglis Andrejs, Trusinskis Karlis, Jegere Sanda, Frick Barbara, Fuchs Dietmar   +7 more
doaj   +1 more source

Nature-inspired radical pyridoxal-mediated C–C bond formation [PDF]

Pyridoxal-5\u27-phosphate (PLP) and derivatives of this cofactor enable a plethora of reactions in both enzyme-mediated and free-in-solution transformations.
Kevin, Skinner, Paul, Zimmerman, Philipp, Gemmel, Sarah, Champagne, Ye, Wang, Alison, Narayan   +5 more
core   +1 more source

Washed Microbiota Transplantation Improves Chronic‐Phase Febrile Infection‐Related Epilepsy Syndrome: The First Case Report With Long‐Term Follow‐Up and Integrated Multi‐Omics Analysis

Microbiota Medicine Research, EarlyView.
ABSTRACT Background Febrile infection‐related epilepsy syndrome (FIRES) is a catastrophic epileptic encephalopathy. Survivors often enter a chronic phase characterized by drug‐resistant epilepsy, cognitive impairment, behavioral and psychiatric symptoms, and long‐term functional disability.
Qianqian Li, Xiao Ding, Sheng Zhang, Faming Zhang   +3 more
wiley   +1 more source

Structural and Biochemical Characterization of the Diaminopimelate Epimerase DapF From Pseudomonas aeruginosa PA14

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The emergence of antibiotic resistance in bacteria is a major threat to global public health. To combat increasingly drug‐resistant bacteria like Pseudomonas aeruginosa, new targets for pharmaceuticals need to be explored. One such potential target for P.
Philipp Schneider, Claudia Hanko, Konrad Büssow, Stefan Schmelz, Wulf Blankenfeldt   +4 more
wiley   +1 more source

Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.

PLoS ONE, 2019
L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong, Hyeonseok Jin, Jeong Ho Chang   +2 more
doaj   +1 more source

A pH‐Responsive fluorescence lifetime probe reveals GOT1 phase separation in cellular anti‐senescence

Smart Molecules, EarlyView.
Acidic pH triggers GOT1 phase separation via IDR1, recruiting ME1 to form ROS‐scavenging condensates that combat senescence, revealed by a FLIM‐based pH probe. Abstract Cellular senescence involves progressive acidification, but how cells sense and adapt to this pH shift remains unclear.
Ziyue Chen, Jiaqi Li, Yan Bao, Mengmeng Wang, Haoyan Chen, Mingjiong Zhang, Lina Ding, Shuangshuang Wu, Baoxing Shen   +8 more
wiley   +1 more source

Pyridoxal Azomethine Salts

, 2019
© 2019, Pleiades Publishing, Ltd. The reactions of 4-methylpiperazin-1-amine, 2-amino- and 4-aminomethylpiperidines with pyridoxal afforded the corresponding azomethines.
Burilov A., Kibardina L., Pudovik E., Bagautdinova R., Pudovik M.   +4 more
core  

Discovery and Characterization of Pyridoxal 5’-Phosphate-Dependent Cycloleucine Synthases [PDF]

Pyridoxal 5’-phosphate (PLP)-dependent enzymes are the most versatile biocatalysts for synthesizing non proteinogenic amino acids. a,a-disubstituted quaternary amino acids, such as 1-amino-1-cyclopentanecarboxylic acid (cycloleucine), are useful building
David A., Delgadillo, Kaushik , Seshadri, Lygia S., de Moraes, Kyle K., Nagasawa, Hosea M., Nelson, Masao, Ohashi, Samuel , Johnson, Yi, Tang, Abner N. D., Abad, Mengting, Liu   +9 more
core   +2 more sources