Results 81 to 90 of about 21,954 (152)

Embracing the future: Neonatal screening for epileptic syndromes

open access: yes
Epilepsia, EarlyView.
Rima Nabbout, Mathieu Kuchenbuch
wiley   +1 more source

Perspectives on the interpretation of mitochondrial responses during skeletal muscle disuse‐induced atrophy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Common human and rodent muscle disuse models and associated changes in skeletal muscle mitochondrial function; respiration, redox stress and apoptotic cell death. I–V, complexes I–V; ETF, electron transfer flavoprotein; Q, Q cycle; C, cytochrome c; Pi, inorganic phosphate; ROS, reactive oxygen species.
Luca J. Delfinis   +2 more
wiley   +1 more source

HR‐MS Analysis of the Covalent Binding of Edaravone to 5‐Formylpyrimidine Bases and a DNA Oligonucleotide Containing a 5‐Formylcytidine Residue

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 14, 30 July 2025.
ABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Romain Regnault   +5 more
wiley   +1 more source

The role of pyridoxine as a countermeasure for in-flight loss of lean body mass [PDF]

open access: yes
Ground based and in flight research has shown that humans, under conditions of microgravity, sustain a loss of lean body tissue (protein) and changes in several biological processes including, reductions in red blood cell mass, and neurotransmitters. The
Gilbert, Joyce A.
core   +1 more source

Improving Egg Quality in Tropical Environments: Assessing the Maize Meal Replacement by Wheat Bran and Soybean Oil in Laying Hen Diets

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
This study demonstrates that replacing maize meal with wheat bran (WB) in laying hen diets, with or without soybean oil, maintains egg quality while enhancing economic performance through increased profitability and contribution margins. The results suggest that WB can be effectively utilized in monogastric animal feeding systems.
Mariana Novela   +11 more
wiley   +1 more source

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

Commentary: Revisiting Physiological and Theoretical Dimensions of Stable Isotope Variation in Human Tissues

open access: yesAmerican Journal of Human Biology, Volume 37, Issue 6, June 2025.
ABSTRACT Typically used to reconstruct diets and migration histories, isotope ratios in human tissues also reflect physiological states associated with health and stress. The publication in 2013 of a paper in the American Journal of Human Biology reviewing such cases has been widely cited.
Laurie J. Reitsema
wiley   +1 more source

Effect of an antiandrogenic H2 receptor antagonist on hepatic regeneration in rats [PDF]

open access: yes, 1988
Because biochemical 'feminization' of the liver in males is observed with hepatic regeneration and because the hepatic regenerative response in females is greater than that in males, the posibility that antiandrogens might potentiate liver regeneration ...
Chapchap, P   +7 more
core  

Functionalized Polydopamine Nanoparticles: A Promising Drug Delivery Platform for the Treatment of Tuberculosis

open access: yesDrug Development Research, Volume 86, Issue 4, June 2025.
ABSTRACT Tuberculosis (TB) is considered a major infectious disease by the World Health Organization. The WHO estimates that there are 1.8 million TB deaths, and 10.4 million new cases of the disease reported yearly. While there are conventional therapies for TB, they have drawbacks such as a lengthy pill regimen, rigorous scheduling, and protracted ...
Nnamdi Ikemefuna Okafor   +3 more
wiley   +1 more source

Influence of α‐Linolenic Acid on the Intestinal Barrier Integrity and Intestinal Antioxidant Status in Broilers

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
A summary of the findings and proposed mechanism of dietary α‐linolenic acid on the intestinal barrier integrity and intestinal antioxidant status in broilers. In this study, we discovered that the administration of ALA effectively enhances intestinal barrier function and improves intestinal antioxidant status in broilers. These effects were attributed
Ao Kang   +6 more
wiley   +1 more source

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